摘要
白细胞介素-15（IL-15）是一种多功能的细胞因子，是T细胞、B细胞、自然杀伤（NK）细胞、淋巴因子激活杀伤（LAK）细胞等细胞活化因子及诱导分泌细胞因子，有刺激造血干细胞增殖分化、增强免疫和抗肿瘤等作用。IL—15具有与白细胞介素-2（IL-2）类似的结构和功能，但许多活性作用强于IL-2，其与肿瘤的发生发展密切相关，且在肿瘤生物治疗方面有广阔的应用前景。
Interleukin-15 is a multifunctional cytokine, which are the activating and induction factors of the T-cell, B-cell, NK-cell and lymphokine-activated killer cell （LAK）. It can stimulate hematopoietic stem cell proliferation and differentiation, enhance immunity and has anti-tumor effects. IL-15 and IL-2 have similar structures and functions, but many activating effects of IL-15 are stronger than the other＇s. IL-15 is closely related to tumor development, and has broad application prospects in biological therapy of cancer.
出处
《国际肿瘤学杂志》
CAS
2011年第9期643-646,共4页
Journal of International Oncology
基金
江苏省自然科学基金资助项目（BK2010579）
