摘要
目的:探讨米非司酮配伍依沙吖啶在妊娠14～26周引产术中的临床效果、用药的安全性。方法:将观察期内198例自愿要求终止妊娠的14～26周育龄妊娠妇女,随机分成观察组和对照组各99例。观察组在羊膜腔内注射依沙吖啶100mg,同时口服米非司酮50mg,对照组仅在羊膜腔内注射依沙吖啶100mg。结果:观察组在用药至宫缩时间、引产成功率比较,两者比较,差异有统计学意义(P<0.05)。胎儿娩出时间、产后出血量、妊娠产物残留、清宫过程均优于对照组,两者差异有统计学意义(P<0.05)。结论:米非司酮配伍乳酸依沙吖啶用于妊娠14～26周引产,成功率高、感染率低,可减少妊娠残留物及产后出血,缩短引产过程,方法简便、安全有效。
Objective：To explore the clinical effects and medication safety of mifepristone matched with ethacridine in induction of labor for 14-26 weeks of pregnancy.Methods：198 cases who were voluntary to terminate pregnancy,required 14 to 26 weeks pregnant women of childbearing age,were randomly divided into observation group and control group 99 cases respectivly.Women in observation group were treated for Intra-amniotic injection of ethacridine 100 mg,while mifepristone 50 mg;the control group was injected only in the amniotic of ethacridine 100 mg.Results：The contraction time was shorter and the success rate of labor induction was higher for the observation group,the difference was significant（P0.05）;The time for baby delivered,postpartum hemorrhage,pregnancy product residue,curettage procedure were all better than the control group,the difference was significant（P0.05）.Conclusion：Mifepristone matched with ethacridine sofhould be used to induce labor of 14 to 26 weeks pregnancy.It has high success rate,low infection rate,reduce the residues of pregnancy and postpartum bleeding,and shorten the induction process.It is safe and effective.
出处
《中国当代医药》
2011年第27期53-54,共2页
China Modern Medicine
关键词
米非司酮
乳酸依沙吖啶
中期妊娠
引产
Mifepristone
Ethacridine
Metaphase pregnancy
Induction of labor
