摘要
目的:探讨维持性血液透析患者微炎症状态与动脉粥样硬化的关系。方法:选择40例维持性HD治疗患者及30例慢性肾功能不全但还未透析患者,用高分辨彩色B超检测患者颈动脉粥样硬化斑块情况,同时测定患者C-反应蛋白(CRP)、ALB、TG、TC、及LDL,分透析组及非透析组,并按斑块情况分为阳性组和阴性组,设健康对照组。结果:透析组CRP比非透析组高,其中斑块阳性组比斑块阴性组明显增高,差别有统计学意义;另外,透析组ALB较非透析组低,TC及LDL均较非透析组高,其中阳性组与非透析组差别有统计学意义。结论:维持性血液透析患者微炎症状态可能是促发动脉粥样硬化的因素之一,控制微炎症状态可能减少动脉粥样硬化的发生。
Objective：Study the relation between microinflammatory state and atherosclerosis in maintenance hemodialysis patients.Methods：40 MHD patients and 30 chronic renal failure patients who had not taken hemodialysis were included.Color Doppler ultrasound was used to examine whether the HD patients had atherosclerosis,meanwhile the levels of CRP,ALB,TG,TC and LDL were tested.The groups were classified as MHD group,NHD group,and plaque-positive group and plaque-negative group.Results：The level of CRP in MHD group is higher than that in NHD group.The level in plaque-positive group is obviously higher than that in plaque-negative group,and there is statistical deference.In addition,the level of ALB in MHD group is lower than that in NHD group,the level of TC and LDL is higher,there is deference between plaque-positive and NHD group.Conclusions：The microinflammatory state may be one of the factors which stimulate the development of atherosclerosis in MHD patients,which may decrease by controlling the microinflammatory state.
出处
《赣南医学院学报》
2011年第4期548-549,共2页
JOURNAL OF GANNAN MEDICAL UNIVERSITY
