摘要
目的探讨和评价无创正压通气(NIPPV)治疗慢性阻塞性肺疾病(COPD)并呼吸衰竭患者的疗效。方法对2009年1月至2010年12月期间在我院给予NIPPV治疗的28例明确诊断为COPD并呼吸衰竭患者的临床病例进行回顾性分析。结果 28例患者使用NIPPV后2h、24h与治疗前比较,动脉血PH值及动脉氧分压(Pa02)均有所提高,二氧化碳分压(Pa02)及呼吸频率(RR)均明显下降,差异有统计学意义(P<0.01);3例患者治疗失败后改为气管插管有创通气,占10.7%(3/28)。结论 COPD并呼吸衰竭应用无创正压通气治疗可有效地纠正缺氧及排出二氧化碳,降低呼吸频率,减轻患者痛苦,具有显著疗效。
Objective To evaluate the value of non-invasive positive pressure ventilation（NIPPV）in the treatment of acute exacerbation of chronic obstructive pulmonary disease（AECOPD）with respiratory failure.Methods 28patients with AECOPD were respectively received conventional medical therapy plus NIPPV.The of blood gas analysis and breath rateof patients before and after 2hours and 24hours the treatment were compared.Results The blood gas analysis and breath rate improved significantly after 2hours and 24hours the treatment（P0.05）.Conclusion Non-invasive positive pressure ventilation has positive effects on patients of AECOPD with respiratory failure significantly.
出处
《疾病监测与控制》
2011年第9期538-539,共2页
Journal of Diseases Monitor and Control
关键词
慢性阻塞性肺疾病
呼吸衰竭
无创正压通气
chronic obstructive pulmonary disease
respiratory failure
non-invasive positive pressure ventilation
