摘要
目的观察三维适形放疗对食管癌患者的疗效及其急性毒副反应。方法初治食管癌患者72例，全部接受三维适形放射治疗，治疗剂量为6000～7000cGy，中位处方剂量为6400cGy，200cGy／次，1次／天，5次／周。评价三维适形放疗的效果及其可能的急性毒副作用。结果全组患者完全缓解（CR）45例；部分缓解（PR）26例；无缓解（NR）I例。肿瘤总有效率（CR＋PR）为98．61％。急性放射性肺炎0级44例，l级19例，2级8例，3级1例，4级0例；急性放射性食管炎0级15例，1级38例，2级15例，3级4例，无4级发生。结论三维适形放疗可明显改善食管癌患者的治疗效果，但其远期疗效需进一步观察。
Objective To observe the curative effect and acute adverse reaction of three-dimen- sional conformal radiotherapy to esophageal cancer patients. Methods 72 cases of esophageal cancer, all accepted three-dimensional conformal radiotherapy, filempeutic doses of 6000 to 7000 cGy, median prescribed dose 6400 cGy, 200 cGy per time, 1 time per day, five times per week. We evaluated the effects of three- dimensional conformal radiotherapy and its possible acute adverse reaction toxicity. Results Among all patients, 45 with complete remission （CR; 26 ones with part remission （PR）; No remission （NR） in one. 98.61% for tumor total effectiveness （CR ＋ PR）. Acute radioactive pneumonia 0 level, 44 cases; 19 cases with level l, 8 cases for 2nd level, grade 3 in 1, 4 level, 0; acute radioactive esophagitis 15 in level 0, 38 in level 1, 15 in level 2, 4 in level 3, but none in level 4. Conclusion Three-dimensional conformal radiotherapy can obviously improve the therapeutic effect of esophageal cancer patients, but the long-term efficacy needs further observation.
出处
《国际医药卫生导报》
2011年第18期2234-2236,共3页
International Medicine and Health Guidance News
关键词
三维适形放疗
食管癌
效果观察
Three-dimensional conformal radiotherapy
Esophageal cancer
Curative effectobservation
