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老年人认知功能障碍与颈动脉内膜中层厚度的相关性 被引量:1

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摘要 目的分析老年人认知功能障碍与颈动脉内膜中层厚度(intima-media thickness,IMT)的相关性。方法选择某社区450例老年人为研究对象,进行颈动脉IMT的测量;并采用简易精神状态量表(MMSE)检测患者的认知功能。根据是否有认知功能异常分组,比较两组IMT厚度的差异及IMT与认知功能的相关性。结果认知功能异常组患者的颈动脉IMT明显大于对照组,且随着IMT分级增加,MMSE得分降低。以文化程度分为文盲组、小学组和中学以上组,各组颈动脉IMT与认知功能障碍的程度呈正相关(r=0.45,P<0.05;r=0.47,P<0.05;r=0.49,P<0.05)。结论颈动脉IMT可以作为反映老年人认知功能的敏感指标,对老年患者,应定期复查IMT以及早发现老年人的认知功能障碍。
出处 《中国老年学杂志》 CAS CSCD 北大核心 2011年第17期3282-3283,共2页 Chinese Journal of Gerontology
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