摘要
目的:探讨10种广东本地清热解毒中草药的抗细菌内毒素作用。方法:采用鲎试剂试管凝集反应进行体外抗内毒素实验。结果:所研究的10种广东本地清热解毒中草药,药液浓度为1.0g/mL时,10种中草药均有抗鲎试剂试管凝集反应,均具有抗细菌内毒素的作用;调整浓度为0.5g/mL时,除金扭扣、溪黄草外,其余中草药具有抗细菌内毒素作用;浓度为0.3g/mL时,除金扭扣、溪黄草、岗梅根外,其余中草药具有抗细菌内毒素作用;浓度为0.1g/mL时,田基黄、葫芦茶、救必应具有抗细菌内毒素作用,提示不同的药材存在抗细菌内毒素作用的差异。结论:广东10种本地清热解毒中草药有直接抗细菌内毒素的作用;其中田基黄、葫芦茶、救必应的抗内毒素作用最强、金扭扣、溪黄草的抗细菌内毒素作用较弱。
Objective ： Explore the role of resistance to bacterial endotoxin for ten kinds Chinese herb medicines with the clearing away heat and toxic material in Guangdong area. Methods ： The limulus reagent tests were used in vitro anti - endotoxin agglutinate reaction experiment. Results： Ten kinds Chinese herb medicines with the clearing away heat and toxic material in Guangdong area all have tubal agglutinate reactions of resistance to limulus reagent （ namely, all have anti -bacterial endotoxin actions） when the concentration is in 1.0g/mL. Other Chinese herb medicines have anti -bac- terial endotoxin actions besides Jin niu kou and Xi huang cao when the concentration is in 0.5g/mL and besides Jin niu kou,Xi huang cao and Gang mei gen when the concentration is in 0.3g/mL. Tian ji huang,Hu lu cha and Jiu bi ying have anti -bacterial endotoxin actions when the concentration is in 0. lg/mL. These results point out that the various medicinal materials have different anti - bacterial endotoxin actions. Conclusions ： Ten kinds Chinese herb medicines with the clearing away heat and toxic material in Guangdong area all have the roles of resistance to bacterial endotoxin. Tian ji huang,Hu lu cha and Jiu bi ying have strongest actions. Jin niu kou, Xi huang cao have relatively weak actions.
出处
《中华中医药学刊》
CAS
2011年第9期2030-2031,共2页
Chinese Archives of Traditional Chinese Medicine
基金
广东省中医药局资助项目(2007269)
江门市新会区科技局资助项目(200608)
关键词
广东地区
中草药
清热解毒
细菌内毒素
Guangdong area
Chinese herb medicines
Clearing away heat and toxic material
Baeterial toxin
