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骶管注射不同容量药物治疗椎间盘突出的临床比较 被引量:3

Effects of different sacral canal injection volumes on treating lumber disc herniation
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摘要 目的观察20mL和30mL容量骶管注射治疗腰椎间盘突出症患者对其疼痛及功能改善的影响及并发症。方法将2009年5月至2010年10月东莞市常平人民医院门诊及住院的腰椎间盘突出症患者120例,随机分为20mL组(生理盐水17mL+利多卡因2mL+醋酸泼尼松龙1mL)60例和30mL组(生理盐水27mL+利多卡因2mL+醋酸泼尼松龙1mL)60例,治疗前及治疗后30min、1周和1月应用目测类比评分法(VAS)对疼痛进行评估,治疗前后应用腰椎疾患治疗成绩评分表对腰椎功能状态进行临床评定。结果 20mL组和30mL组治疗前,VAS评分分别为(7.5±1.5)分和(7.7±1.5)分。注射治疗后30min及l周VAS评分,20mL组分别为(5.2±0.8)分和(4.5±0.5)分,30mL组分别为(5.1±1.0)分和(4.6±0.4)分,两组止痛效果比较,差异均无统计学意义(t=2.359,2.362,P>0.05)。两组患者平均改善指数及平均改善率接近,30mL组较20mL组出现下肢麻木、头晕、尿潴留、呕吐等并发症显著。结论骶管注射有利于腰椎间盘突出症患者缓解疼痛、改善症状,恢复日常生活能力,但注射用量不与效果成正比。 Objective To observe the effect of sacral canal injection on pain relief, function im- provement and complications for patients with lumber disc herniation, which volume was 20 mL and 30 mL. Methods All the 120 outpatients and inpatients diagnosed with lumber disc herniation from May 2009 to October 2010 were divided into two groups, the 20 mL ( saline 17 mL + lidocaine 2 mL + prednisolone 1 mL) group ( n = 60), the 30 mL ( saline 27 mL + lidocaine 2 mL + prednisolone 1 mL) group ( n = 60 ). Then visual analogue scales (VAS) scores were evaluated before treatment and 30 minutes, the seventh day, thirti- eth day after treatment, to assess lumbar functional status by lumbar disorders scores on the score sheet be- fore and after treatment. Results VAS scores of the 20 mL group and the 30 mL group before treatment were (7.5 ± 1.5 ) and (7.7 ±1.5 ) points. On the 30 minutes, seventh day after treatment VAS scores in 20 mL group were (5.2 ±0.8) and (4.5±0.5) points,in the 30 mL group were (5.1± 1.0) and (4.6 ±0.4) points, and analgesic effects of the two groups were compared, the differences being not significant ( t=- 2. 359, 2. 362, P 〉 0.05 ). The mean improvement index and the average improvement rate of the 20 mL group and the 30 mL group were close to each other, but the incidence rate of lower extremity numbness, dizziness, urinary retention, vomiting and other complications in the 30 mL group were significantly more than those in the 20 mL group. Conclusion Sacralcanal injection in patients with lumbar disc herniation is helpful for pain relief, improving symptoms and restoring activities of daily living, but the effect is not pro- portional to the injection volume.
出处 《中华损伤与修复杂志(电子版)》 CAS 2011年第4期45-48,共4页 Chinese Journal of Injury Repair and Wound Healing(Electronic Edition)
基金 广东省东莞市医疗卫生单位科研计划项目(200910515025)
关键词 椎间盘突出 腰椎 注射 硬膜外 Disc herniation Lumber Injection Epidural
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