摘要
目的观察滋肾活血方治疗多囊卵巢综合征的临床疗效。方法将60例多囊卵巢综合征患者随机分为治疗组和对照组各30例。治疗组予滋肾活血方,对照组予达英-35,均治疗6个月。观察各组治疗前、治疗6个月后及停药3个月经周期血清黄体生成素(LH)、卵泡刺激素(FSH)、睾酮(T)水平及卵巢B超的变化情况,并评价临床疗效。结果停药3个月经周期后,治疗组、对照组临床总有效率分别为96.7%7、0.0%;组间临床疗效比较,差异有统计学意义(P<0.05)。治疗组、对照组妊娠例数分别为4例(13.3%)0、例(0.0%),组间差异有统计学意义(P<0.01)。组内比较,治疗组治疗前后FSH、LH、T水平差异有统计学意义(P<0.05,P<0.01),停药3个月经周期较治疗后的各项指标差异无统计学意义(P>0.05);对照组治疗前后LH、T水平差异有统计学意义(P<0.05,P<0.01),停药3个月经周期较治疗后T水平差异有统计学意义(P<0.05)。组间同期比较,治疗后及停药3个月经周期各项指标差异均有统计学意义(P<0.05,P<0.01)。治疗组治疗前后卵泡数大于10个的病例数分别为15例、1例,对照组为14例、5例;治疗后组间差异有统计学意义(P<0.05)。结论滋肾活血方治疗PCOS,近期、远期疗效良好。
Objective To observe the clinical efficacy of ＂ Kidney-Nourishing and Blood-Activating Decoction＂ in the treatment of polycystic ovary syndrome （PCOS）. Methods Sixty cases of PCOS were randomly divided into treatment group with 30 patients and control group with 30 patients. The treatment group was given ＂Kidney-Nourishing and Blood-Activating Decoction＂, and the control group was treated with diane-35, both groups with a course of six nnmths. The changes of levels of serum LH, FSH, and T and ovary b-ultrasound were observed before treatment, right after and three menstrual cycles after treatment. Results After discontinuing treatment for 3 menstrual cycles, the total effective rates of the treatment group and the control group were 96.7% and 70.0% respectively, with a statistical significance between the two groups（ P 〈 0.05 ）. The pregnant cases of the treatment group and the control group were 4 （ 13.3% ） and 0 （0.0v2） respectively, and there was a statistical significance in the comparison of the two groups（ P 〈 0.01 ）. In the treatment group, the levels of FSH, LH and T had significant differences between before and after treatment（P 〈 0.05 ,P 〈 0.01 ）, and had no difference between after treatment and discontinuing treatment after 3 menstrual cycles （ P 〉 0.05 ）. In the control group, the levels of LH and T had significant differences between before and after treatment （ P 〈 0.05, P 〈 0.05 ）, and the level of T also had a significant difference between after treatment and discontinuing treatment after 3 menstrual cycles（ P 〉 0.05 ）. Betbre the treatment, there was no statistical at significance between the two groups in the levels of FSH, LH and T （ P 〉0.05 ）. However, statistical significances were iound in the levels of FSH, LH and T after the treatment and discontinuing treatment after 3 menstrual cycles（P 〈 0.05）. Before and after treatment, cases of more than 10 follicles were 15 and 1 respectively in the treatment group, and were
出处
《上海中医药杂志》
2011年第9期48-50,共3页
Shanghai Journal of Traditional Chinese Medicine
基金
上海市重点学科建设项目(S30303)
关键词
多囊卵巢综合征
闭经
滋肾活血
月经
临床研究
Polycystic ovary syndrome
amenorrhoea
nurishing kidney and activating blood
menstruation
clinical study
