摘要
目的:观察芪白平肺胶囊对慢性阻塞性肺病(COPD)致肺动脉高压患者血气的影响。方法:选择COPD致肺动脉高压患者200例,按随机数字表法分为对照组和治疗组各100例,在基础治疗的基础上,分别用硝苯地平和芪白平肺胶囊予以治疗,观察患者安全性指标和血气分析、纤维蛋白原变化。结果:两组治疗后动脉血氧分压(PaO2)均明显提高,动脉血二氧化碳分压(PaCO2)均明显降低(P<0.01),两组间有显著差异。两组治疗后纤维蛋白原均明显降低(P<0.01),治疗组与对照组相比有显著性差异(P<0.01),治疗组明显优于对照组;治疗组治疗后红细胞压积明显降低(P<0.01),对照组无改变,两组有显著性差异(P<0.01),治疗组明显优于对照组。结论:芪白平肺胶囊可明显改善慢阻肺痰瘀阻肺证患者缺氧状况。
Objecttive To observe the blood-gas analysis Effect of Qibai Pingfei capsule Cured PAH based COPD’s Patients.Methods：200 patients were randomly diuided into to 2 groups.The treatment group were treated with Qibai Pingfei capsule,and the control group were treated with nifedipine.Blood-gas analysis and FIB were observed.Results：Blood-gas analysis were significantly between two groups（P〈0.01 or P〈0.05） after 14 days.Conclusion：Qibai Pingfei capsule has the effect on improving lack oxygen of PAH based COPD.
出处
《中医学报》
CAS
2011年第9期1037-1039,共3页
Acta Chinese Medicine
基金
国家重点基础研究发展计划(973计划)(编号:2008CB517404)
安徽高校省级自然科学研究重点项目(编号:KJ2010A215)
关键词
芪白平肺胶囊
慢性阻塞性肺病
血气分析
硝苯地平
肺动脉高压
Qibai Pingfei capsule
chronic obstructive pulmonary disease
blood -gas analysis
pulmonary arterial hypertension
