摘要
目的探讨地诺前列酮栓用于妊娠引产的临床效果及安全性。方法正常单胎头位足月妊娠、具有引产指征而无使用地诺前列酮栓禁忌证的孕妇62例,常规阴道放入地诺前列酮栓10 mg,观察置药12,24 h宫颈评分的变化、宫缩情况及用药到临产所需时间、胎心及羊水变化、分娩方式及剖宫产指征、药物不良反应。结果地诺前列酮栓促宫颈成熟的效果明显,用药12 h后宫颈Bishop评分(7.23±2.25)分,用药24 h后宫颈Bishop评分(9.76±3.02)分。引产成功60例(96.77%),母婴安全,不良反应少。结论地诺前列酮栓使用简单,疗效好,安全性高,可控性强,增加自然分娩的概率,可降低剖宫产率,是比较安全的促宫颈成熟药。
Objective To study the efficacy and safety of dinoprostone suppository for odinopoeia. Methods 62 cases of full-term singleton pregnant women with fetal head down had odinopoeia indications without using dinoprostone suppository were conventionally placed in the vagina with 10 mg dinoprostone suppository. The cervix uteri was observed after 12 and 24 h, uterine contraction and duration to labor, the fetal heart rate changes, amniotic fluid delivery, cesarean signs and adverse drug reactions were detected. Results The dinoprostone suppository obviously promoted cervical ripening with Bishop score 12 h after medication as （7.23±2.25）, and 24 h as （9.76±3.02）. The dinoprostone suppository made high abortion rate and was safety for mother and child with few adverse reaction. Conclusion Dinoprostone suppository is simple to use, effective, high security, controllable. It increases opportunities for natural labor, reduces caesarean section rates, which is a safe cervical ripening enhancer.
出处
《医药导报》
CAS
2011年第9期1155-1156,共2页
Herald of Medicine
关键词
地诺前列酮栓
促宫颈成熟
引产
Dinoprostone suppository
Promote cervical ripening
Odinopoeia
