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二肽基肽酶4(DPP-4)抑制剂治疗2型糖尿病的最新进展(一) 被引量:3

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摘要 1.传统2型糖尿病治疗陷入困境 糖尿病(Diabetes mellitus,DM)是一组病因和发病机理尚未完全明确的内分泌-代谢综合征,其特点是慢性高血糖,伴随因胰岛素(Insulin)分泌及/或作用缺陷所引起的糖、
出处 《中国制药信息》 2011年第9期6-11,共6页
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  • 1张幼怡.二甲双胍的心脏保护作用机制研究进展[J].中国医学前沿杂志(电子版),2011,3(5):21-23. 被引量:8
  • 2威尔斯伯,李力华.DPP-Ⅳ抑制剂--研究现状及研发方向(上)[J].糖尿病天地.临床刊,2009,3(4):188. 被引量:1
  • 3Pan CY,Yang W,Tou C,et al.Efficacy and safety of saxagliptin indrug-nave Asian patients with type 2 diabetes mellitus:a random-ized controlled trial[J].Diabetes Metab Res Rev,2012,28(3):268-275. 被引量:1
  • 4Pfützner A,Paz-Pacheco E,Allen E,et al.Initial combination ther-apy with saxagliptin and metformin provides sustained glycaemiccontrol and is well tolerated for up to 76 weeks[J].Diabetol ObesMetab,2011,13(6):567-576. 被引量:1
  • 5Hollander PL,Li J,Frederich R,et al.Safety and efficacy of saxa-gliptin added to thiazolidinedione over 76 weeks in patients withtype 2 diabetes mellitus[J].Diab Vasc Dis Res,2011,8(2):125-135. 被引量:1
  • 6Chacra AR,Tan GH,Apanovitch A,et al.Saxagliptin added to asubmaximal dose of sulphonylurea improves glycaemic control com-pared with uptitration of sulphonylurea in patients with type 2 dia-betes:a randomised controlled trial[J].Clin Pract,2009,63(9):1395-1406. 被引量:1
  • 7Iwamoto Y,Taniguchi T,Nonaka T,et al.Dose-ranging efficacy ofsitagliptin,a dipeptidyl peptidase-4 inhibitor,in Japanese patientswith type 2 diabetes mellitus[J].Endocr J,2010,57(5):383-394. 被引量:1
  • 8Lim S,An JH,Shin H,et al.Factors predicting therapeutic efficacyof combination treatment with sitagliptin and metformin in type 2diabetic patients[J].Clin Endocrinol(Oxf),2012,77(2):215-223. 被引量:1
  • 9Dobs AS,Goldstein BJ,Aschner P,et al.Efficacy and safety of sita-gliptin added to ongoing metformin and rosiglitazone combinationtherapy in a randomized,placebo-controlled,54-week trial inpatients with type 2 diabetes[J].J Diabetes,2012. 被引量:1
  • 10DeFronzo RA,Fleck PR,Wilson CA,et al.Efficacy and safety ofthe dipeptidyl peptidase-4 inhibitor alogliptin in patients with Type2 diabetes and inadequate glycemic control:a randomized double-blind,placebo-controlled study[J].Diabetes Care,2008,31(12):2315-2317. 被引量:1

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