摘要
目的:探讨垂体后叶素不同使用方法在宫颈冷刀锥切术中的手术效果和患者术后恢复情况。方法:132例宫颈上皮内瘤样变(CIN)Ⅲ及累及腺体患者均行宫颈冷刀锥切术,其中术中两点注射垂体后叶素组(研究1组)48例,单点注射垂体后叶素组(研究2组)44例,未使用垂体后叶素组(对照组)40例,比较3组的手术时间、术中出血量、术后住院天数、术后出血量及出血天数等。结果:研究1、2组手术时间、术中阴道出血量、术后住院天数、术后阴道出血量、排液时间及出血天数均明显少于对照组(P均<0.01),研究1组手术时间、术中及术后阴道出血量少于研究2组(P均<0.05)。研究1、2组和对照组1年内宫内妊娠者分别为64.3%(18/28)、64.0%(16/25)和45.0%(9/20),研究组与对照组1年内宫内妊娠率差异有统计学意义(P<0.05)。使用垂体后叶素的患者无1例不良反应发生。结论:宫颈冷刀锥切术中应用垂体后叶素注射,能明显减少术中出血,缩短手术时间,并减少住院天数,降低术后并发症,2种方法均安全可靠,两点注射法优于单点注射法。
Objective： vasopressin different use in the cervical cold knife conization of the effect of surgery and postoperative recovery. Methods： 2005 to January-December 2010 more hospital gynecology colposcopy biopsy diagnosis of CIN Ⅲ and involving 132 patients gland, underwent cervical cold knife conization, divided into three groups, two of which surgery point injection of vasopressin group （study group 1） in 48 cases, single point injection of vasopressin group （study group 2） 44 cases and did not use vasopressin group （control group） 40 cases. Compared three groups of operative time, blood loss, postop- erative hospital stay, postoperative bleeding and bleeding and number of days. Results. The study group 1 and group 2 study of surgical time, blood loss, postoperative hospital stay, postoperative complications, postoperative bleeding and number of days of bleeding were significantly less than the control group （P〈0.01）, Study 1 group, operative time, intraoperative and postoperative bleeding is less than study group 2 （P〈0.05）, studied two groups of postoperative hospital stay, number of days of bleeding and Research Group 1 showed no significant difference （P〉0.05）. Use of vasopressin in patients with non-one cases of adverse reactions. Conclusions： The cold-knife conization of cervical application of vasopressin injection, can significantly reduce blood loss, shorter operative time and reduced hospital stay, reduced postoperative complications, including two single-point injection method is superior to injection, Both methods are safe and reliable.
出处
《海南医学院学报》
CAS
2011年第10期1419-1421,1424,共4页
Journal of Hainan Medical University
基金
海南医学院科研基金资助学报项目(0020110394)~~
