摘要
目的探讨生长抑素在肠梗阻治疗中的应用效果。方法回顾性分析2005年1月至2010年12月本科收治114例肠梗阻患者,其中常规治疗(对照组)58例,常规治疗基础上加生长抑素(治疗组)56例,治疗组生长抑素(每天6 mg静脉微泵滴注维持72 h)比较两组治疗前后的临床症状及体征改善情况、胃肠减压量、中转急诊手术率。结果治疗组临床症状明显改善,与对照组相比,48 h腹痛和腹胀的缓解率分别为76.8%、56.9%(P<0.05);肛门恢复排气排便比率分别为78.5%、58.6%(P<0.05);胃肠减压量明显少于对照组,分别为(212±125)mL/d、(517±134)mL/d(P<0.05),急诊手术率明显低于对照组,分别为10.7%、44.8%(P<0.05)。结论在常规治疗基础上应用生长抑素治疗肠梗阻能加快症状缓解,提高保守治疗的成功率,降低急诊手术率。
Objective To discuss the application of somatostatin in the treatment for the intestinal obstruction.Methods 114 intestinal obstruction patients from Jan.2005 to Dec.2010 were included into the study.The 114 patients were put into 2 groups： 56 patients in the treatment group and 58 patients in the control group.The treatment group received somatostatin in addition to the conventional therapy.Then the improvement of clinical symptom and physical sign,gastrointestinal decompression capacity and emergency operation rate were compared between the 2 groups.Results The treatment group′s clinical symptoms were obviously improved.The remission rate of stomachache and abdominal distension after 48h was 76.8% in the treatment group and 56.9% in the control group（P0.05）;the recovery rates of passage of gas by anus was 78.5% in the treatment group and 58.6% in the control group（P0.05）;the gastrointestinal decompression capacity was（212±125）mL/d in the treatment group and（517±134）mL/d in the control group（P0.05）;the emergency operation rate was 10.7% in the treatment group and 44.8% in the control group（P0.05）.Conclusion The somatostatin in addition to the conventional treatment in the therapy for intestinal obstruction could relieve the symptom faster,raise the successful rate of conservative treatment and lower the emergency operation rate.
出处
《医学综述》
2011年第16期2538-2539,共2页
Medical Recapitulate
关键词
生长抑素
肠梗阻
疗效
Somatostatin
Intestinal obstruction
Therapeutic effect
