摘要
目的观察伊曲康唑间歇冲击疗法和序贯疗法治疗甲真菌病的临床疗效。方法 51例患者根据治疗药物的不同分为伊曲康唑组和序贯疗法组,分别在治疗疗程结束后3个月、6个月和24个月进行真菌学检查、临床疗效和再发率观察。结果伊曲康唑组远期临床有效率为84.62%、序贯疗法组为92.00%,两组差异无统计学意义(P>0.05);伊曲康唑组24个月再发率为35.29%、序贯疗法组为5.00%,两组差异有统计学意义(P<0.05)。结论两组均取得较好疗效,但序贯疗法组相比伊曲康唑组具有再发率低的优势。
Objective To evaluate the efficacy of itraconazole pulse therapy and sequential therapy in the treatment of tinea unguium.Methods There 51 cases with tinea unguium were divided into itraconazole group and sequential group.The efficacy were recorded 3 months and 6 months after treatment.The rate of recurrence were recorded 24 months after treatment.Results The effective rates were 84.62% and 92.00% in itraconazole group and sequential group,without significant defferences between the two groups（P0.05）.The rates of recurrence in itraconazole group and sequential group were 35.29% and 5.00%,showing significant defferences（P0.05）.Conclusion Itraconazole pulse therapy and sequential therapy are effective on tinea unguium and the recurrence rate of sequential therapy is lower than itraconazole pulse therapy.
出处
《中国热带医学》
CAS
2011年第8期1008-1009,共2页
China Tropical Medicine
