摘要
目的:探讨丙泊酚复合瑞芬太尼靶控输注(target controlled infusions,TCI)在产科患者全身麻醉中的应用价值及安全性评价。方法:46例均选自2008-2010年我院麻醉科行全麻手术产科者,采用丙泊酚复合瑞芬太尼麻醉诱导,气管插管后行机械通气,维持麻醉用微量泵持续输注瑞芬太尼、丙泊酚、派库溴铵,监测并记录患者诱导前、诱导后10min、手术开始时、术中30min、术毕的血压(SBP/DBP)、心率(HR)、SpO2、苏醒时间及术后疼痛情况,观察整个手术过程不良反应。结果:诱导10min时HR较诱导前明显下降,差异有统计学意义(P<0.05);SBP/DBP诱导后10min开始下降,手术开始时未继续下降,术中及术毕血压平稳。2例患者术中30min时血压下降明显,予以输血补液后好转。所有患者SpO2均>96%,术后苏醒时间(24±8.66)min,术中未发生躁动、谵妄和呼吸抑制等不良反应。结论:丙泊酚复合瑞芬太尼靶控维持在全身麻醉中,对产科患者循环影响小,不良反应少,安全性较高。
Objective:To investigate the effect of disoprofol target controlled infusion for general anesthesia in obstetrics patients.Methods:46 cases in our department were treated by reapropofol and remifentanil target controlled infusion,anesthesia was induced with pine rocuronium,propofol and remifentani1 and then the patients were mechanically ventilated after tracheal intubation,and anesthesia was maintained by pumping propofol,pine rocuronium and remifentanil.Monitoring and recording blood pressure,heart rate,oxygen saturation before induction,after 10min,beginning of operation,intraoperative 30min and end of operation,recovery time and postoperative pain.Observed side effects during the entire procedure.Results:Heart rate was significantly decreased compared with induction after 10min,the difference was statistically significant(P0.05).SBP/DBP declined after induction 10min,but it did not continue to decline beginning of operation.Blood pressure was stable after surgery.The blood pressure significantly decreased in two patients,It was improved after blood transfusion.Oxygen saturation of all patients were above 96%.The postoperative recovery time was(24±8.66)min,There was no agitation,delirium and respiratory depression and other adverse reactions.Conclusion:Because of the stable circulatory system,less untoward effects and awaking up in time,propofol and remifentanil target-controlled in general anesthesia is safe and manageable in obstetrics patients.
出处
《医学理论与实践》
2011年第15期1773-1774,共2页
The Journal of Medical Theory and Practice