摘要
探讨缺血修饰白蛋白(IMA)、Hcy、Hs-CRP、cTnI、Mb和B型钠酸肽(BNP)水平在急性冠状动脉综合征(ACS)早期诊断中的价值。选择胸痛患者小于3h内、6h测定血清IMA、Hcy、Hs-CRP、cTnI、Mb和BNP水平,并与对照组比较。结果表明,3h组IMA和Mb水平与对照组相比差异有统计学意义(P<0.01),其他4指标与对照组相比差异无统计学意义(P>0.05),而6h组IMA、Hcy、Hs-CRP、cTnI、Mb和BNP水平与对照组相比差异均有统计学意义(P<0.01)。IMA是反映心肌缺血早期诊断的灵敏指标,对发病小于3h的ACS患者更有价值,IMA与Hcy、Hs-CRP、cTnI、Mb和BNP联测,有助于ACS的早期诊断。
To explore the clinical value of levels of serum ischemia modified albumin（IMA）,Hcy,Hs-CRP,Mb,cardiac troponin I（cTnI） and BNP in the patients with acute coronary syndrome（ACS）.The levels of serum IMA,Hcy,Hs-CRP,cTnI,Mb and BNP in 100 patients with ACS within 3h after onset of chest pain and once again at 6h,and 50 health controls were determined.The results showed that the levels of serum IMA and Mb in 3h group were obviously higher than those in the control group（P0.01）,but there was no significant difference in others between 3h group and control group.The levels of serum IMA,Hcy,Hs-CRP,cTnI,Mb and BNP in 6h group were significantly higher than those in the control group（P0.01）.The serum IMA was a very sensitive diagnostic marker for early detection of myocardial ischemia,especially within 3h after onset of chest pain.Combined detection of IMA,Hcy,Hs-CRP,cTnI,Mb and BNP may have a high practical clinical value in the early diagnosis of ACS.
出处
《标记免疫分析与临床》
CAS
2011年第4期224-227,共4页
Labeled Immunoassays and Clinical Medicine
