摘要
目的探讨卵巢交界性肿瘤（BOT）的临床特点。方法对术后病理确诊为BOT的60例患者的临床特点、临床分期、癌变潜能、病理类型、血清CA125阳性率进行分析。结果病理类型以浆液性囊腺瘤为主，占60．0％（36160）；浆液性囊腺瘤局灶癌变发生率[22．2％（8，36）]明显高于黏液性囊腺瘤E5．3％（1／19）]（P〈0．05）。血清CA125阳性率为51．7％（31，60）。BOT伴微浸和BOT伴局灶癌变CA125阳性率[65．O％（13，20）和81．8％（9/11）]均明显高于单纯BOT[31．0％（9／29）]（P〈0．05），而BOT伴微浸与BOT伴局灶癌变CA125阳性率比较差异无统计学意义（P〉0．05）。结论BOT具有低度恶性潜能，因临床症状不典型，术前诊断困难，并且CA125对单纯BOT不敏感。育龄女性应定期行超声检查有无卵巢肿物，术前结合血清CA125检测可对BOT伴微浸以及伴局灶癌变者行术前预测诊断，积极尽早手术治疗，术中行快速病理检查，以减少癌变风险。
Objective To investigate the clinical features of borderline ovarian tumor （BOT）. Method The clinical features, clinical stage, malignant potential, pathological type, the positive rate of serum CA125 were analyzed in 60 patients with pathological diagnosis of BOT. Results Serous cystadenoma was the main pathological type, accounted for 60.0% （36/60）. The occurrence of focal canceration in serous cystadenoma [ 22.2% （8/36）] was higher than that in mucinous cystadenoma [5.3% （ 1/19 ）] （P 〈 0.05 ）. The positive rate of CA125 was 51.7%（31/60）. The positive rate of CA125 in BOT with micro-dip or focal eanceration [65.0%（13/20） and 81.8%（9/11）] was higher than that in simple BOT [ 31.0% （9/29）] （P 〈 0.05 ）, but there was no significant difference between BOT with miero-dip and BOT with focal eanceration （P 〉 0.05）. Conclusions BOT is low malignant potential and preoperative diagnosis is difficult because of the typical clinical symptoms. CA125 is not sensitive to pure BOT. Women of childbearing age should regularly check for ovarian tumor by ultrasonography and preoperative serum CA125 test can be combined with micro-dip on the BOT and those made with preoperative focal predict cancer diagnosis. Aggressive surgical treatment is necessarily as soon as possible and rapid intraoperative pathological examination to reduce cancer risk.
出处
《中国医师进修杂志》
2011年第24期17-19,共3页
Chinese Journal of Postgraduates of Medicine
