摘要
目的通过对小阴唇粘连患儿的病因调查，为寻找预防措施提供依据。方法2010年3—12月重庆医科大学附属儿童医院共诊治小阴唇粘连患儿100例，为实验组，同期在儿保科就诊未患本病的同龄女婴100例为对照组，收集并分析两组临床资料，包括尿布使用、会阴护理、体重、尿常规检查，检测实验组雌激素水平。结果实验组100例，就诊时年龄最小2个月，最大58个月，平均14．5个月，其中2～12个月60例，12～24个月24例，24～36个月14例，36—58个月2例。病因调查：①体重：实验组超重16例，对照组超重14例，P〉0．05；②尿路感染：实验组有尿路感染病史3例，尿常规提示感染1例，对照组有尿路感染史1例，尿常规提示无感染病例，P〉0．05；③尿pH值：实验组尿pH≤6．0者68例，对照组43例，P〈0．01；④会阴区清洁护理：尿布类型：实验组长期使用传统尿布67例，对照组49例，P〈0．01；尿不湿更换：实验组中及时更换者8例（24．2％），对照组24例（47．1％），P〈0．05；会阴清洗：实验组每日清洗会阴2次以上者4JD例，对照组中63例，P〈0．01；开裆裤的使用：实验组中1岁以上40例中继续使用开裆裤者35例（87．5％），对照组中52例中仅23例（44．2％），P〈0．01。⑤雌二醇水平：实验组雌二醇水平低于正常值29例，其中3例复发患儿雌二醇水平低于正常值。结论小阴唇粘连是由多种因素作用的结果，其中雌激素水平、尿液酸碱度、会阴部清洁及是否早期使用封挡裤等为发病相关因素，与尿路感染、肥胖、外阴损伤无明显相关。加强婴幼儿外阴的清洁护理，适当碱化尿液有可能减少小阴唇粘连的发生。
Objective To research the cause of labial adhesion and find the preventive measure, we assess the clinical data of labial adhesion, and compare with normal prePubertal girl. Methods Compare the clinical data of labial adhesion with normal prepubertal girl, including daily cleaning care of vulva, diaper change, urinary tract infection histroy, weight and routine analysis of urine, etc. Measure the serum estradiol level in the girls with labial adhesions. Results From march 2010 to december 2010, we treatment 100 patients with labial adhesion in the out-patient department of urology. Except 2 patients found at brith, the rest were found and treatmented in 2 months after. The mean age of the studied population was 14.5months （ range,2 to 58 months）. Cause investigation： （1）The rate of extraweight in those with labial adhesion is higher than in control（ P 〉 0.05 ）, （2）The rate of urinary tract infection histroy in labial adhesion is higher than in control （P 〉 0.05 ） , （3）The rate of urinary pH ≤6.0 in labial adhesion is higher than in control （ P 〈 0.01 ）, （4）Chinese traditionaldiper in those with labial adhesion is more common than in control（ P 〈 0.01 ）. The rate of diper changing timly in labial adhesion is lower than in control（ P 〈 0.05 ）. The rate of cleaning the vulva daily in labial adhesion is lower than in control（ P 〈 0. 01 ）. The open-seat pants in those with labial adhesion is more common than in control（ P 〈 0.01 ）. （5）The incidence of hypoestrogenism in labial adhesion is 28% （ 28 of 100 patients）, and the level of estrogen in 3 recrudescence is low. Conclusion Labial adhesion is the result of multiple factors. Hypoestrogenism ,low urinary pH and incorrect daily cleaning care of vulva take place in the development of labial adhesion. Recurrent urinary tract infection, obesity,injury of vulva and family histry have small relationship with labial adhesion. Enhancing the correct daily cleaning care could reduce the incidence of lab
出处
《临床小儿外科杂志》
CAS
2011年第4期260-262,共3页
Journal of Clinical Pediatric Surgery
