摘要
目的:观察重症急性胰腺炎(SAP)患者经胃镜置放鼻空肠营养管行肠内营养的疗效观察。方法:将50例患者随机分为2组:①全肠外营养(TPN)组26例,行常规治疗:禁食、胃肠减压、抑酸、抗炎、生长抑素、全肠外营养及对症治疗等;②肠内营养(EN)组24例,在常规治疗的基础上,入院后3d左右经胃镜置放鼻空肠营养管,逐渐停止肠外营养,改行肠内营养。比较2组患者在治疗前及治疗后10、20d血红蛋白、血清总蛋白、血清白蛋白、血钙水平变化,统计平均住院天数及住院费用,观察感染发生率、病死率。结果:EN组均一次性置管成功,无明显并发症。治疗20d后EN组血红蛋白较TPN组明显提高(P<0.05)。EN组住院时间、住院费用及感染发生率明显低于TPN组(P<0.05)。结论:SAP患者置放空肠营养管行肠内营养的治疗效果好,方法安全。
Objective： To observe the therapeutic effect of indwelling nasojejunal feeding tube through gastroscope in patients with severe acute pancreatitis （SAP）. Methods： Fifty patients were randomized divided into two groups： （1） 26 cases of total parenteral nutrition （TPN） group underwent routine therapy： fasting, gastrointestinal decompression, acid suppressing, anti-infection, somatostatin, and parenteral nutrition, etc, （2） On the basis of routine therapy, 24 cases of enteral nutrition （EN） group were indwelled nasojejunal feeding tube through gastroscope about 3 days after admission. Then, the parenterat nutrition was gradually stopped and switched to EN. Changes of levels of patients＇ hemoglobin, serum total protein, serum albumin and blood calcium were compared before treatments and 10, 20 days after treatments. Average length of hospital stay and costs were calculated, and the rate of infection and mortality were observed. Results： Patients in EN group underwent one-time catheterization successfully without obvious complications. Level of hemoglobin was elevated obviously in EN group than that in TPN group 20 days after treatment （P〈0. 05）. Hospital stay, hospital costs and rate of infection were obviously lower in EN group than those in TPN group （P〈0. 05）. Conclusions： Indwelling nasojejunal feeding tube through gastroscope is effective and safe in patients with SAP.
出处
《内科急危重症杂志》
2011年第4期206-207,226,共3页
Journal of Critical Care In Internal Medicine
关键词
重症急性胰腺炎
鼻空肠营养管
全肠外营养
肠内营养
Severe acute pancreatitis Nasojejunal feeding tube Total parenteral nutrition gnteral nutrition
