摘要
目的研究吉兰-巴雷综合征的神经电生理特点,探讨F波在GBS早期诊断中的作用。方法回顾性研究准北市人民医院在2005年至2009年中被诊断为吉兰-巴雷综合征并且接受过神经电生理检查的47例患者,对其进行运动神经传导速度(MCV)、F波及感觉神经传导速度(SCV)检测,共检测329条运动神经及235条感觉神经,F波329条,并对结果进行分析。结果在发病1周内54%患者的F波出现不正常,而运动传导速度减慢者仅有6%,38%的患者运动末端潜伏期延长,57%患者复合运动动作电位波幅下降,30%患者的感觉动作电位波幅下降或消失,21%患者感觉传导速度减慢,未发现传导阻滞的患者。结论吉兰-巴雷综合征患者早期F波较神经传导速度变化更为敏感,表现为出现率下降、潜伏期延长,有助于临床早期诊断。
Objective To explore the characteristics of electrodiagnostic abnormalities of Guillain-Barre syndrom（GBS） and to discuss the value of F wave in early diagnosis of GBS.Methods We retrospectively reviewed the neurophysiological studies of 47 patients with GBS discharged from our hospital in 2005 to 2009.We study the motor and sensory nerve conduction velocity and F wave.The total number of nerves studied was 329 for motor nerve,235 for sensory nerve,329 for F wave.Results In the first week from onset,the characteristics of electrodiagnostic abnormalities was 54% patients with abnomal F wave,6% patients with slowed motor nerve conduction velocity,38% patients with prolonged distal lantency,and 57% patients with declined amplitude of compound nerve action potention,30% patients with declined amplitude of sensory nerve action potential,21% patients with slowed sensory nerve conduction velocity.None of patient have conduction block.Conclusion In the early stage of GBS,especially with the pathology type of demyelination,F wave is more sensitive than nerve conduction velocity and distal lantency.The prolonged of F wave lantency and declined of frequency is helpful in the early diagnosis of GBS.
出处
《临床医学》
CAS
2011年第5期22-23,共2页
Clinical Medicine
