摘要
目的探讨女性早发冠心病患者的冠状动脉病变特点及其相关危险因素。方法 116例经冠状动脉造影确诊的冠心病患者,根据年龄分为早发冠心病组65例和非早发冠心病组51例。对2组患者的相关临床资料进行回顾性统计分析,比较2组的冠状动脉病变特点、吸烟史、血脂水平、冠心病家族史、高血压病史、糖尿病病史、饮酒史等。结果早发冠心病组的冠心病家族史阳性率及三酰甘油水平均高于非早发冠心病组,均有显著性差异(P均<0.05);而高血压病史、糖尿病史发生率均低于非早发冠心病组,但均无显著性差异(P均>0.05)。早发冠心病组患者常以急性冠脉综合征起病(66%),冠状动脉病变多为单支病变(44%),非早发冠心病组以多支病变为主。结论冠心病阳性家族史、高三酰甘油均在女性早发冠心病的发生发展中起着重要作用。
Objective It is to approach the pathological changes feature of coronary artery in female patients with premature coronary heart disease（CHD） and its correlative risk factors.Methods One hundred and sixteen patients with CHD who were made a definite diagnosis through coronary arteriongraphy were divided into two groups according to age.Sixty-five cases were in premature CHD group and fifty-one cases were in non-premature CHD group.The correlative clinical data of the two groups were analyzed retrospectively.The pathological changes feature of coronary artery,smoking history,blood fat level,CHD family history,hypertension history,diabetes mellitus history and drinking history of the two groups were compared.Results The male rate of CHD family history and TG level in premature CHD group were both higher than those in non-premature CHD group and the differences were both significant（both P0.05）.The incidence rates of hypertension history and diabetes mellitus history in premature CHD group were both lower than those in non-premature CHD group but the differences were both not significant（both P0.05）.The patients in premature CHD group often onste as coronary artery syndrome（66%） and most of coronary artery pathological changes were single ramus pathological change（44%）.The pathological changes in non-premature CHD group were more ramus pathological changes mainly.Conclusion Both the male CHD family history and the increased TG level might play an important role in the development of female premature CHD.
出处
《现代中西医结合杂志》
CAS
2011年第26期3266-3267,3300,共3页
Modern Journal of Integrated Traditional Chinese and Western Medicine
关键词
早发冠心病
冠状动脉
女性
premature coronary heart disease
coronary artery
female
