摘要
目的:按照维吾尔医学体液论对冠心病患者进行异常体液辨证证分型,观察血管舒缩功能在不同异常体液型冠心病患者中的变化,从而为冠心病的维医异常体液辨证分型和防治提供实验基础。方法:根据维吾尔医学体液论对确诊为冠心病的305例患者进行异常体液辨证分型(分组),采用硝酸还原酶法、放免法检测冠心病患者血清一氧化氮(NO)、血浆内皮素(ET)和血管紧张素II(AgII)含量。结果:305例冠心病患者中异常黑胆质型冠心病70例,异常血液质型冠心病126例,异常胆液质型冠心病28例,异常黏液质型冠心病81例。各组冠心病患者ET、NO、AgⅡ含量与健康对照组比较均有显著性差异(P<0.05或P<0.01);异常血液质组、异常胆液质组及异常黏液质组之间两两比较,均无显著性差异(P>0.05);异常黑胆质组与其他3组之间进行两两比较,发现异常黑胆质组与其他各组之间均有显著性差异(P<0.05)。结论:不同异常体液型冠心病患者血管舒缩功能均有异常变化,但异常黑胆质型冠心病患者血管舒缩功能变化较其他异常体液型(非异常黑胆质型)冠心病患者更为明显。
Objective： To classify the Coronary Heart Disease （CHD） patients by the theory of Traditional Uighur Medicine （TUM） , observe the changes of vascular systolic and diastolic function in different Abnormal Humour syndrome patients with CHD, and provide experimental foundation for the classification, prevention and control of CHD by the Abnormal Humour Theory in TUM. Methods： The Humour Theory of TUM was used to classify 305 cases of CHD patients. Slightly acid reductase and RIA methods were used to measure the concentrations of endothelin （ET） , nitric oxide （NO） , angiotensin Ⅱ （ Ag Ⅱ）. Results： There were 70 cases of Abnormal Savda syndrome, 126 cases of Abnormal Khan syndrome, 28 cases of Abnormal Sapra syndrome, 81 cases of Abnormal Balgham syndrome among the 305 cases of CHD patients. The concentrations of ET, NO, Ag Ⅱ in various types of Abnormal Humour syndrome patients with CHD were significantly different from those of normal controls （P 〈 0. 05 or P 〈 0. 01 ）. No significant differences of ET, NO and Ag Ⅱ level were discovered while the three groups of non Abnormal Savda patients compared with each other （P 〉 0.05）. However, the concentrations of ET, NO and Ag Ⅱ in Abnormal Savda syndrome group were significantly higher than those of other groups （P 〈 0.05）. Conclusion： It is concluded that concentrations of ET, NO and Ag Ⅱ in various types of Abnormal Humour syndrome patients with CHD are abnormally changed, the abnormality in the Abnormal Savda syndrome patients with CHD are more serious than the three other types.
出处
《中国中医基础医学杂志》
CAS
CSCD
北大核心
2011年第8期891-893,共3页
JOURNAL OF BASIC CHINESE MEDICINE
基金
国家中医药管理局中医药科技专项(06-07MZ14)
国家自然科学基金资助项目(30660237)
