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重度窒息新生儿血浆N端脑钠肽水平及纳美芬干预效果的观察 被引量:1

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摘要 目的:探讨重度窒息新生儿血浆NT-proBNP水平及纳美芬干预对NT-proBNP水平的影响。方法:选择用Ap-gar评分法诊断新生儿窒息,观察重度窒息新生儿52例,分A组:纳美芬干预治疗组27例;B组:常规治疗组25例。C组:非窒息对照组30例。在用药治疗前及纳美芬干预治疗1d、3d后分别采用化学发光方法检测各组血浆NT-proBNP水平。结果:3组用药前血浆NT-proBNP水平均高于正常水平;A、B两组用药1d、3d后血浆NT-proBNP水平较前降低,A组较B组下降更加明显。两组在同一时间点血浆NT-proBNP水平相比差异有统计学意义(P<0.05)。结论:重度窒息新生儿血浆中氨基末端脑钠肽前体(NT-proBNP)的水平升高,纳美芬干预治疗可降低血浆NT-proBNP水平,具有脑保护作用。
作者 赵丽华
出处 《贵阳中医学院学报》 2011年第4期116-118,共3页 Journal of Guiyang University of Chinese Medicine
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