摘要
以廉价的亚磷酸三乙酯为配体,首次用于Cu催化的碘代芳烃和末端炔烃的偶联反应,考察了不同Cu盐、金属纯度、碱和催化剂用量等条件对反应性能的影响.结果表明,当以高纯度的CuI(99.999%)为铜源,催化剂用量为5mol%时,在KOH作用下,该催化体系成功催化了一系列碘代芳烃和末端炔烃的反应,表现出良好的催化活性,此外,该催化体系还可用于2-苯基苯并呋喃的合成,为该类化合物的合成提供了一条较为经济的途径.
The commercially available ligand P（OCH2CH3）3 was first used in the copper catalyzed cross-coupling reaction of aryl iodides with alkynes.The influences of different copper salts,metal purity,bases,and catalyst dosages were investigated.The results indicate that the coupling of a broad range of aryl iodides with alkynes can be catalyzed by the system of 5 mol% CuI/P（OCH2CH3）3 efficiently.In addition,this catalyst also exhibits good activity in the synthesis of 2-phenyl-benzofuran in one pot,which provides an economical way for the syn-thesis of similar compounds.
出处
《催化学报》
SCIE
EI
CAS
CSCD
北大核心
2011年第8期1376-1379,共4页
