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癫痫患者脑部螺旋CT血流灌注成像研究 被引量:3

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摘要 目的探讨癫痫患者脑部螺旋CT血流灌注成像参数及其意义。方法收集24例癫痫患者,继发性癫痫20例,选其病灶中心平面为靶层面,脑部无显性病灶的原发性癫痫4例,选颞叶及基底节交界平面为靶层面,行CT脑灌注扫描,收集BF、BV、MTT、PS等参数值,与正常参照参数标准值及对侧对称部位正常脑部血流灌注成像的参数值进行对比。结果 20例继发性癫痫中,脑膜瘤、转移瘤、胶质瘤三者BV、BF、PS值均增高,以脑膜瘤最明显,呈显著高灌注,PS值最大,转移瘤次之。脑梗死灶及软化灶BF降低,MTT延长,PS值明显减低。4例原发性癫痫患者中,2例的颞叶参数双侧略有差异,一侧BF、BV、PS略升高,MTT无差异;2例BF、BV、MTT、PS值无差异。结论螺旋CT血流灌注成像参数值可以表达癫痫患者的脑部血流动力学变化,间接反映出脑部血流的状况与癫痫发生的关系,对癫痫的分析探索了一条新的路径。
机构地区 南昌市第二医院
出处 《江西医药》 CAS 2011年第7期660-662,共3页 Jiangxi Medical Journal
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