摘要
目的探讨体重指数(body mass index BMI)是否是女性骨质疏松症(Osteoporosis OP)的危险因素。方法收集2008年9月～2010年12月因腰腿疼痛在三峡大学第一临床医学院(宜昌市中心人民医院)康复科就诊的500例女性患者资料,经X线检查判断无骨质增生232例,采用法国DMS公司生产的双能X线骨密度仪测定腰椎(L2-4)正位骨密度(bone mineral density,BMD),记录其身高、体重(计算体重指数)、症状、运动、吸烟、饮酒等影响因素;测定腰椎(L2-4)骨密度,明确是否骨质疏松(OP);用t检验及χ2检验比较骨质疏松症组和非骨质疏松症组的影响因素,用Logistic回归分析对象中各种可能影响骨质疏松症的因素及骨质疏松症发生的相关性。结果骨质疏松症组和非骨质疏松症组比较:体重指数、运动情况、吸烟、饮酒比例有显著差异;根据多因素分析,体重指数、吸烟是骨质疏松症的危险因素,运动与偶尔饮酒是骨质疏松症的保护因素。BMI每增加一个单位,女性发生骨质疏松的风险增加2.003(P=0.034)。结论体重指数是女性骨质疏松的危险因素。
Objective To explore whether body mass index is one of the risk factors of osteoporosis in women. Methods Clinical data of 500 female patients with wrist and leg pain in Department of Rehabilitation Medicine, the First College of Clinical Medical Science （Center Hospital of Yichang） , Three Gorges University from September 2008 to December 2010 were collected. There were 232 female patients with non-hyperostosis diagnosed using X-ray. Bone mineral density （BMD） of L2-4 was measured using a dual energy absorptiometry （DMS, France）. The related factors including height, body weight （calculated BMI） , symptoms, exercise frequency, smoking, and drinking were recorded. BMD of the lumbar spine was determined to judge osteoporosis status. The influential factors between osteoporosis group and non- osteoporosis group were compared using t test or X2 test. The relationship of multiple factors with osteoporosis was analyzed using logistic regression. Results There were significant differences among BMI, exercise, smoking, and drinking. According to the logistic regression results, BMI and smoking were risk factors of osteoporosis, and exercise and occasional drinking were protection factors of osteoporosis. The risk of osteoporosis increased by 2. 003 times in women with BMI scaling up by 1 unit （P = 0. 034）. Conclusion BMI is a risk factor of osteoporosis in females.
出处
《中国骨质疏松杂志》
CAS
CSCD
2011年第8期683-686,共4页
Chinese Journal of Osteoporosis
基金
三峡大学第一临床医学院科研发展基金项目(KFJ2009025)
关键词
女性
骨质疏松症
体重指数
骨密度
Female
Osteoporosis
Body mass index
Bone mineral density
