摘要
目的评价国产注射用利福平冻干粉针(维夫欣)治疗结核性脑膜炎的临床有效性和安全性,并与利福平胶囊比较。方法将55例肺结核患者随机分为利福平冻干粉针组和利福平胶囊组对照,观察疗效。结果利福平冻干粉针组疗效确切且较口服利福平组胃肠道副作用少,起效更快。结论利福平冻干粉针在结核性脑膜炎的治疗中具有局部药物浓度高,作用快,副作用小的特点,有较好的临床应用价值。
Objective To evaluate the domestic injectable rifabutin freeze-dried needle（weaver hin） treatment of tuberculous meningitis clinical efficacy and safety,and rifampacin capsule comparison.Methods will 55 patients with tuberculosis patients were randomly divided into rifabutin freeze-dried needle group and rifampacin capsule group contrast,observe the curative effect.Results rifabutin freeze-dried needle curative effect of exact and more oral rifabutin group gastrointestinal side effects less,the effect-acting faster.Conclusion rifabutin freeze-dried needle in the treatment of tuberculous meningitis with local drug concentration high effect,fast,side effect was small characteristics,has good value of clinical applications.
出处
《临床肺科杂志》
2011年第9期1408-1410,共3页
Journal of Clinical Pulmonary Medicine
关键词
利福平注冻干粉针
结核性脑膜炎
治疗
rifabutin note freeze-dried needles
Tuberculous meningitis
treatment
