摘要
目的评价术后镇痛中氟比洛芬酯对吗啡用量和效果的影响。方法手术患者60例,随机均分为三组。术后镇痛:A组,吗啡40 mg+阿扎司琼10 mg+生理盐水100 ml;B组用氟比洛芬酯50 mg超前镇痛,术后吗啡40 mg+阿扎司琼10 mg+生理盐水100 ml;C组氟比洛芬酯100 mg+阿扎司琼10 mg+吗啡40 mg+生理盐水100 ml。观察术后吗啡的用量,患者自控镇痛(PCA)总次数,术后4、8、12、24 h的VAS疼痛评分。结果与A组比较,B、C组术后122、4 h吗啡用量减少,PCA总次数减少,VAS评分降低(P<0.05)。结论氟比洛芬酯50 mg超前镇痛或镇痛泵中氟比洛芬酯100 mg与吗啡配伍,具有较好的镇痛效果,可减少吗啡用量。
Objective To evaluate the effects of flurbiprofen on the analgesia and requirement of morphine during patient-controlled intravenous analgesia（PCIA）.Methods PCIA was performed in 60 patients underwent surgeries,who were randomly and equally divided into 3 groups of A（morphine 40mg＋azasetron 10mg＋normal saline 100ml）,B（50mg flurbiprofen preemptive analgesia and postoperative morphine 40mg＋azasetron 10mg＋normal saline 100ml）,and C（flurbiprofen 100mg＋azasetron 10mg＋morphine 40mg＋normal saline 100ml）.The morphine consumption,PCA number and VAS scores at 4,8,12,24h during PCIA were recorded.Results Compared to group A,the morphine consumption and PCA number were less,and VAS scores were lower in groups of B and C（P〈0.05）.Conclusion Preemptive analgesia with flurbiprofen 50mg or flurbiprofen 100mg added to PCIA solution with morphine has a satisfactory analgesia and reduced requirements of morphine during postoperative pain relief.
出处
《江苏医药》
CAS
CSCD
北大核心
2011年第15期1793-1795,共3页
Jiangsu Medical Journal
关键词
氟比洛芬酯
吗啡
术后镇痛
Flurbiprofen
Morphine
Postoperative analgesia
