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膝骨关节炎骨赘放射学大小与负重位下肢力线相关性分析 被引量:12

Correlation between osteophytes size and limb alignment of weight-bearing position in the knees of osteoarthritis patients
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摘要 [目的]探讨膝OA患者膝关节放射学骨赘大小与负重位下肢力线的关系。[方法]对40例接受人工全膝关节置换术的原发性骨关节炎患者(共40膝),利用躯体X线测量系统进行负重位下肢力线的测量。将膝关节正位X线片导入计算机,应用Photoshop软件长度测量工具分别测量股骨远端、胫骨平台宽度和骨赘长度。骨赘长度与骨端宽度的比值,称为骨赘突起指数。应用SPSS软件通过Pearson相关检验,评价测量者内及测量者间骨赘突起指数重复性,探索膝OA患者膝关节放射学骨赘大小和负重位下肢力线之间的关系。[结果]40例膝OA患者负重位下肢力线平均为:12.53°±5.62°。测量者内及测量者间骨赘突起指数有较好相关性,r接近1(P<0.001)。负重位下肢力线与股骨内侧髁骨赘突起指数呈正相关(r=0.530,P<0.001),与胫骨平台内侧骨赘突起指数呈正相关(r=0.618,P<0.001)。负重位下肢力线与股骨外侧髁(r=-0.008,P=0.961)、胫骨平台外侧(r=0.244,P=0.129)骨赘突起指数间无相关性存在。[结论]膝OA患者股骨内侧髁骨赘突起指数、胫骨平台内侧骨赘突起指数与负重位下肢力线呈正相关,机械应力通过生物化学因素促使骨赘的形成可能是此现象的原因。 [Objective] To assess the correlation between osteophytes size and limb alignment of weight-bearing position in the knees of osteoarthritis patients. [Methods]A total of 40 knees in 40 patients were obtained from individuals undergoing total knee arthroplasty due to severe primary osteoarthritis.The limb alignment of weight-bearing position was measured using body X film measuring-system(BXFMS).A special scale method called the "spur index" was devised to determine a corrected measurement of the osteophyte size in this study.The intra-observer and inter-observer repeatability of the "spur index" were tested by Pearson correlation.The correlation between limb alignment and osteophytes size was evaluated by Pearson correlation. [Results]The average angle of lower limb alignment was 12.53°±5.62°in the weight-bearing position of 40 patients.The comparison of the measured values between the intra-observer and inter-observer showed a good repeatability(r=1,P0.001).There was a positive correlation between the weight-bearing limb alignment and the osteophyte size of the medial femoral condyle(r=0.530,P0.001).The osteophyte size of the medial tibial plateau was positively correlated with the weight-bearing limb alignment(r=0.618,P0.001).But no correlation was found between the weight-bearing limb alignment and the osteophyte size of the lateral femoral condyle(r=-0.008,P=0.961),as well as between the weight-bearing limb alignment and the osteophyte size of the lateral tibial plateau(r=0.244,P=0.129). [Conclusion]The result of this study indicates that there is a positive correlation between the weight-bearing limb alignment and the osteophyte size of the medial femoral condyle,as well as between the weight-bearing limb alignment and the osteophyte size of the medial tibial plateau.This finding may be explained by the fact that mechanical stress contributes to osteophyte formation through biochemical factors.
出处 《中国矫形外科杂志》 CAS CSCD 北大核心 2011年第15期1279-1283,共5页 Orthopedic Journal of China
基金 山西省重点实验室开放基金资助项目(编号:2009011059-9) 山西省青年科技研究基金资助项目(编号:2010021034-5)
关键词 骨关节炎 骨赘 突起指数 下肢力线 osteoarthritis osteophyte spur index limb alignment
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参考文献28

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