摘要
目的:建立离子色谱法测定中药西瓜霜硫酸盐的含量。方法:采用IonPac(AS11-HC色谱柱和DIONEXA SRS(300 4-mm抑制器,以30 mmo.lL-1氢氧化钠为淋洗液,流速为1.0 mL.m in-1,进样量100μL,电导检测器进行检测,西瓜霜的含量以硫酸钠计。结果:硫酸钠进样量在1.1～111.7μg.mL-1范围内线性关系良好(r=1.000);平均加样回收率为99.9%(n=9)。结论:本方法操作简单,灵敏度和准确性较高,可用于西瓜霜的质量控制。
Objective：To establish a new method for determination of mirabilitum praeparatum by ion chromatography.Method：The IonPac AS11-HC column was eluted with 30 mmol·L-1 of NaOH solution at the flow rate of 1.0 mL·min-1,injection volume was 100 μL,and analytes were detected conductively with DIONEX ASRS 300 4-mm suppressor.The content of the preparation was calculated in sulfates.Results：A good linearity of sodium sulfate in water melon frost was obtained at 1.1-111.7 μg·mL-1 with the correlation coefficent of 1.000.The average recovery was 99.9%（n=9）.Conclusion：The developed method was proved to be simple,sensitive,accurate,appropriate for the quality control of sulfates content in mirabilitum praeparatum.
出处
《药物分析杂志》
CAS
CSCD
北大核心
2011年第8期1549-1551,共3页
Chinese Journal of Pharmaceutical Analysis
关键词
硫酸盐
西瓜霜
离子色谱
测定
sulfates
mirabilitum praeparatum
ion chromatography
determination
