摘要
目的了解临床分离的铜绿假单胞菌(PAE)的耐药情况,指导临床合理用药。方法对医院2008年1月-2009年12月,临床各科室送检的标本中分离的264株铜绿假单胞菌药敏结果进行统计分析。结果 264株铜绿假单胞菌临床科室分布ICU占36.0%、脑外伤占24.8%、呼吸内科占20.7%、泌尿外科占4.2%、内分泌科占3.4%、其他占10.9%;对常用抗菌药物的耐药率阿米卡星为17.4%,亚胺培南为20.8%、美罗培南为18.9%、头孢他啶为34.9%、头孢曲松为62.9%、头孢噻肟为67.8%,对哌拉西林/他唑巴坦、头孢哌酮/舒巴坦、阿米卡星、左氧氟沙星等抗菌药物有较高的敏感率。结论临床分离的PAE对常用抗菌药物不同程度耐药,应加强其耐药性检测,合理应用抗菌药物。
OBJECTIVE To understand drug resistance of Pseudomonas aeruginosa（PAE） isolated form clinics,and to guide the reasonable use of antibiotics.METHODS A total of 264 strains of PAE submitted form various departments from Jan 2008 to Dec 2009 were collected for drug susceptibility test,the results were analyzed.RESULTS Of 264 PAE strains,36.0% distributed in ICU,department of cerebral surgery（24.0%）,Respiratory medicine（20.7%）,urology（4.2%）,endocrinology 3.4% and others 10.9%;the drug resistance rates of PAE to commonly used antibiotics were： amikacin（17.4%）,imipenem（20.8%）,meraopenem（18.9%）,ceftazidime（34.9%）,ceftriaxone（34.9%） and cefotaxime（67.8%）,and were highly sensitive to piperacillin/sulbactam,cefoperazone/sulbactam,amikacin and levofloxacin.CONCLUSION PAE has various resistance degrees to commonly used antibiotics.The monitoring to its resistance should be strengthened to reasonably use antibiotics.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2011年第15期3253-3254,共2页
Chinese Journal of Nosocomiology
关键词
铜绿假单胞菌
医院感染
抗菌药物
耐药性
Pseudomonas aeruginosa
Nosocomial infection
Antibiotics
Drug resistance
