摘要
目的调查住院精神分裂症患者代谢综合征的发生率,分析与代谢综合征有关的危险因素。方法以2008年1月—12月郑州市第八人民医院符合CCMD-3诊断标准的精神分裂症患者出院病例为研究对象,代谢综合征的诊断标准采用2004年医学会糖尿病分会代谢综合症标准。了解精神分裂症患者代谢综合症的发生率,用Logistic回归分析影响发生的相关因素。结果符合条件共入组完成726例,精神分裂症患者中代谢综合征患病率32.3%。代谢综合征患病相关的危险因素有年龄、氯氮平及精神分裂症的病程(P<0.05)。Logistis回归分析结果显示,精神分裂症患者伴发代谢综合症的危险因素是高龄,病程。结论与普通人群相比,精神分裂症患者具有较高的代谢综合症患病风险,可能的危险因素有高龄,病程长和服用氯氮平等。
Objective To evaluate the prevalence of metabolic syndrome （MS） in schizophrenics and explore the relative factors. Methods We conducted a cross - sectional study of schizophrenics from inpatients in the eighth people＇ s hospital of Zhengzhou in 2008. The diagnosis of MS was estab- lished with the criteria of branch of diabetes mellitus of Chinese Medical Association. Results Among 726 schizophrenic, there were 235 cases（32.3% ） suffered from metabolic syndrome. Single -factor analysis showed that age, duration of the disease, the classification of antipsychotics（clozapine） , were at high risk of metabolic syndrome. Logistic regression analysis appeared that metabolic syndrome correlated with age duration of the disease. Conclusions The metabolic syndrome is highly prevalent among patients with schizophrenia and is strongly associated with age, longer duration of schizophrenia and clozapine.
出处
《医药论坛杂志》
2011年第11期35-37,共3页
Journal of Medical Forum
