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电针联合氟西汀对卒中后抑郁症患者抑郁状态及神经功能的影响 被引量:17

Effects of electric-acupuncture and fluoxetine on depression and neurological function of post-stroke depression patients
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摘要 目的观察电针联合氟西汀对卒中后抑郁症(PSD)患者抑郁状态及神经功能的影响。方法将95例PSD患者随机分为A、B、C三组,分别采用电针、氟西汀、电针联合氟西汀治疗。治疗前后根据哈密顿抑郁量表(HAMD)、神经功能缺损量表及副反应量表(TESS)评分,评定其抑郁程度、神经功能缺损程度及不良反应。结果治疗6周后,三组治疗前后组内及治疗后组间HAMD评分、神经功能缺损评分、TESS评分比较均有统计学差异(P均<0.05),其中C组优于A组及B组(P均<0.05)。结论电针联合氟西汀能更好地改善PSD患者的抑郁状态,促进其神经功能恢复,且不良反应少,值得临床应用。 Objective To evaluate the effects of electric-acupuncture and fluoxetine on depression and neurological function of post-stroke depression(PSD) patients.Methods A total of 95 patients with PSD were randomly divided into the group A,B and C,they were treated with electric-acupuncture,medicine,and electric-acupuncture combined with medicine respectively.The degree of depression and neurological function defect,side-effects were evaluated by hamilton depression scale(HAMD),the clinical neurological function defect scale and the treatment emergent symptom scale(TESS) before and after treatment.Results After treatment for 6 weeks,HAMD scores,the clinical neurological function defect scale and TESS scores were significantly different in 3 groups(P0.05),which in the group C was much better than those in group A and B(P0.05).Conclusion Electric-acupuncture combined with fluoxetine could regulate depression and improve neurological function and reduce side effects of medicine in treating PSD patients.It is deserved to be applied to clinical use.
出处 《山东医药》 CAS 北大核心 2011年第25期9-11,共3页 Shandong Medical Journal
基金 南通市社会发展科技计划项目(S2006051)
关键词 卒中后抑郁症 氟西汀 电针 哈密顿抑郁量表 临床神经功能缺损量表 electric-acupuncture fluoxetine post-stroke depression hamilton depression scale clinical neurological function defect scale
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