摘要
背景:TNM分期对胃癌疗效评估和预后判断至关重要。目的:评价内镜超声(EUS)在胃癌术前TNM分期中的临床应用价值。方法:87例胃癌患者术前1周行EUS和螺旋CT(HCT)检查,参考手术和术后病理评价EUS和HCT行胃癌TNM分期的准确性。结果:EUS判断胃癌T分期的总体准确率为81.6%;EUS判断N0和N1分期的准确率与HCT接近(P>0.05),但判断N2和N3分期的准确率较HCT明显下降(P<0.05);EUS判断M分期的总体准确率低于HCT(P=0.000),但判断M0分期的准确率与HCT相当。结论:EUS在评价胃癌术前T分期中的临床应用价值较高,但判断N2、N3和M分期的准确性还有待提高,要获得较准确的胃癌术前TNM分期以指导临床治疗方案的选择,有必要联合CT等检查。
TNM staging is crucial for predicting the treatment efficacy and prognosis of gastric cancer. Aims： To assess the clinical value of endoscopic ultrasonography （EUS） in preoperative TNM staging of gastric cancer. Methods： EUS and helical CT （HCT） were performed 1 week preoperatively in 87 patients with gastric cancer for estimating the accuracies of EUS and HCT in TNM staging with operational and pathologic results as references. Results： The overall accuracy rate of EUS in assessing the T staging of gastric cancer was 81.6%. There were no significant differences in the accuracy rates of EUS and HCT in assessing the NO and N1 staging （P〉0.05）, however, the accuracy rates of EUS in assessing the N2 and N3 staging were significantly lower than those of HCT （P〈0.05）. The overall accuracy rate of EUS in assessing M staging was lower than that of HCT （P=0.000）, but no differences in accuracy rates were seen for M0 staging. Conclusions： The clinical application of EUS is useful in preoperative T staging of gastric cancer, but there is still much room for improving the accuracies of EUS in N2, N3 and M staging. CT or other techniques should be used in association for increasing the accuracy of preoperative TNM staging to guide the choice of treatment modality.
出处
《胃肠病学》
2011年第6期348-350,共3页
Chinese Journal of Gastroenterology
