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感觉神经端侧吻合的再生轴突功能 被引量:4

The functions of regenerated axons in end to side neurorrhaphy
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摘要 目的:探讨感觉神经端侧吻合后再生有功能轴突的可能性.方法:新西兰兔15只,左侧耳大神经作为供神经,取自右耳的神经移植体作为受神经,受神经的一端与供神经作端侧吻合,另一端植入失神经支配的皮瓣.正常皮肤和未植神经的皮瓣作为对照组,每组动物5只,4mo后用神经单纤维放电技术观察皮瓣内再生神经纤维放电数量、分布和类型.结果:皮瓣内各类感觉纤维放电均有发生,放电纤维总数达到正常皮肤组的58%,主要分布在神经植入区.未植入神经的对照组,仅在皮瓣边缘有少量放电.结论:神经端侧吻合可以再生有功能的轴突. AIM: To probe the possibility of functional sensory endings regeneration after end to side neurorrhaphy. METHODS: Fifteen New Zealand rabbits were used in this study. The left greater auricular nerve served as the donor nerve. A nerve graft taken from the right ear served as the receptive nerve which anastomosed to the donor nerve with the other end implanting into the denervated skin flap. Normal skin and denervated skin flap without nerve implantation served as control groups, with 5 animals in each group. The single nerve fibre recording technique was used to investigate the number, distribution and types of regenerated discharging nerve fibers 4 mouths after operation. RESULTS: The inductive discharges of nerve fibres were observed in all types of regenerated sensory nerves, the total discharging fibers were about 58% of that in normal skin. Few discharging fibers were observed in denervated skin flap without nerve implantation. CONCLUSION: End to side neurorrhaphy can regenerate functional axons.
出处 《第四军医大学学报》 1999年第11期962-963,共2页 Journal of the Fourth Military Medical University
关键词 感觉神经 神经端侧吻合 神经再生 皮瓣 sensory nerve end to side neurorrhaphy nerve regeneration skin flap
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