摘要
注射用辅料聚氧乙烯脱水山梨醇单油酸酯(吐温80)可能是导致多种中药注射剂临床不良反应的主要原因之一。本文在大量的文献调研和实验研究的基础之上,对吐温80的化学结构、基本性质、质量标准、药理活性、安全性评价及毒理研究等方面进行概述,以期为合理选择和使用安全、高效的中药注射用辅料及促进中药注射剂健康发展提供理论依据。
Polysorbate 80 for injection accessories is one of the main reactions of clinical adverse to which may be leaded by a variety of traditional Chinese medicine injection. In this review,on the basis of literature research and experimental studies, polysorbate 80 are summarized in areas which conclude the chemical structure, basic nature,quality standards,pharmacological activity,safety evaluation and toxicity studies. The review aimed to provide theoretical basis for the rational selections of Chinese medicine,safe and efficient usages of injection accessories, and to promote healthy development of traditional Chinese medicine injections.
出处
《中国中药杂志》
CAS
CSCD
北大核心
2011年第14期1910-1915,共6页
China Journal of Chinese Materia Medica
基金
中国中医科学院基本科研业务费自主选题项目(ZZ2010010)
