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米索前列醇联合缩宫素预防产后出血的临床观察 被引量:12

Clinical observation of misoprostol combined with oxytocin for preventing postpartum hemorrhage
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摘要 目的探讨米索前列醇联合缩宫素预防产后出血的效果。方法将68例存在产后出血风险的孕产妇随机分为2组,对照组32例于分娩后常规应用缩宫素,治疗组36例于分娩后直肠给予米索前列醇联合缩宫素治疗。比较2组产后出血发生率及2h和24h的出血量。结果治疗组产后出血率为0低于对照组的15.6%,差异有统计学意义(P<0.05);且治疗组产后2h、24h出血量均少于对照组,差异均有统计学意义(P<0.05)。结论米索前列醇联合缩宫素预防产后出血效果显著,不良反应轻微,值得推广应用。 Objective To investigate the effect of misoprostol combined with oxytocin for preventing postpartum hemorrhage.Methods 68 cases pregnant women with the risk of postpartum hemorrhage were divided into treatment group(36 cases) and control group(32 cases).Control group were treated by oxytocin,treatment group were treated by misoprostol combined with oxytocin.Compared the incidence of postpartum hemorrhage and 2,24h the amount of bleeding of two groups.Results Postpartum hemorrhage rate of treatment group(0) was lower than that of control group(15.6%)(P〈0.05);And postpartum 2,24h bleeding volume of treatment group were less than those of control group(P〈0.05).Conclusion Misoprostol combined with oxytocin for preventing postpartum hemorrhage has significantly effectual,and is worth for generalization.
出处 《临床合理用药杂志》 2011年第15期53-54,共2页 Chinese Journal of Clinical Rational Drug Use
关键词 米索前列醇 缩宫素 产后出血 预防 Misoprostol Oxytocin Postpartum hemorrhage Prevention
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