摘要
目的观察吡格列酮联合门冬胰岛素30治疗2型糖尿病的疗效。方法将55例单独胰岛素治疗3个月以上的2型糖尿病患者按随机数字表法分为对照组(n=25,门冬胰岛素30治疗)与治疗组(n=30,吡格列酮联合门冬胰岛素30治疗),2组患者接受相同的糖尿病教育,疗程均为3个月。观察2组患者治疗前后糖化血红蛋白(HbA1c)、甘油三酯(TG)、胰岛素用量及低血糖发生情况。结果 2组患者治疗后HbA1c、TG及胰岛素用量较治疗前均有改善(P<0.01),治疗组疗效优于对照组(P<0.05或P<0.01);治疗组的低血糖事件少于对照组。结论与单独使用门冬胰岛素30相比,联合应用吡格列酮可以帮助2型糖尿病患者血糖、血脂达标的同时减少胰岛素用量,减少低血糖事件的发生。
Objective It is to observe the effect of Pioglitazone combined with Insulin Aspart 30 on type 2 diabetes mellitus.Methods 55 cases of type 2 diabetes mellitus were randomly divided into two groups,who had received insulin therapy for three months.Control group（n=25） was treated with Insulin Aspart 30,and Treatment group（n=30） treated with Pioglitazone combined Insulin Aspart 30.All of then received the same Diabetes Education,and be treated for three months.Compared HbA1c,TG and Insulin amount in pre and post treatment between two groups.Results HbA1c,TG and Insulin amount of post treatment in two groups had improved than before（P〈0.01）,Treatment group was superior to control group（P〈0.05 or P〈0.01）;Hypoglycemia of treatment group less than that of control group.Conclusion Combined with Pioglitazone can control HbA1c,TG and less Insulin amount of type 2 diabetes mellitus,reduce hypoglycemia.
出处
《实用临床医学（江西）》
CAS
2011年第5期17-18,共2页
Practical Clinical Medicine
