摘要
目的评价部分性脾栓塞联合抗病毒治疗乙肝肝硬化脾功能亢进疗效和安全性。方法对62例乙肝肝硬化脾功能亢进患者,采用脾部分栓塞联合阿德福韦酯治疗,监测血常规、肝功能、血病毒载量及门静脉、脾静脉内径和脾脏厚度等的变化,随访3个月。结果患者治疗后外周血细胞上升、肝功能改善、病毒量下降,脾脏缩小、门静脉压力降低,消化道出血减少。结论脾部分栓塞联合抗病毒治疗乙肝肝硬化脾功能亢进是一种安全、疗效好的方法,值得临床推广和广泛应用。
Objective To evaluate the curative effect and safety of partial splenic artery embolization combined with antiviral therapy to hypersplenism of hepatitis B cirrhosis.Methods Sixty-two patients with hypersplenism of hepatitis B cirrhosis accepted partial splenic artery embolization combined with Adefovir Dipivoxil therapy.At the same time,changes of blood routine,hepatic function,blood viral load,spleen thickness and internal diameter of portal vein and splenic vein were detected and followed for 3 months.Results After therapy,peripheral blood cell rose and hepatic function improved.Patients＇blood viral load lowered and spleen shrinked.Meanwhile,portal venous pressure of patients decreased and alimentary tract hemorrhage reduced.Conclusion Partial splenic artery embolization combined with antiviral therapy to hypersplenism of hepatitis cirrhosis is safe and eutherapeutic and worth widespread use.
出处
《中外医疗》
2011年第18期19-20,共2页
China & Foreign Medical Treatment
关键词
脾动脉栓塞
抗病毒
乙型肝炎
肝硬化
脾功能亢进
Splenic Artery Embolization
Antiviral
Hepatitis B
Cirrhosis
Hypersplenism
