摘要
目的：为进一步探讨中药诱导细菌Ｌ型及其临床意义。方法：用大黄、黄连、丹参、板蓝根生药制成１０％煎剂。经药敏试验（Ｋ－Ｂ纸片法）与筛选，尔后再以不同浓度稀释经纸片法诱导金葡菌、痢疾杆菌、大肠杆菌形成Ｌ型。结果：经药敏试验筛选，三种中药浓度均在４０ｍｇ／片和５０ｍｇ／片诱导Ｌ型菌落及形态较典型。结论：大黄、黄连、丹参可使痢疾杆菌、大肠杆菌形成Ｌ型，提示临床用中药治疗急、慢性感染无效时，也要注意检查是否细菌变为Ｌ型及必要时调整用药，以免造成疾病迁延与再发。
Objective: To make a further study of the induction of L-type bacteria with the traditional Chinese herbs and its clinical significance. Methods: A 10% decoction was made up from coptis chinensis,paeonol,and soon.After the skin test and screening,the decoction was diluted at different concentrations so that staphylococus aureus,Bacillus dysenteriae and Bacillus coli could be induced to form bacteria L. Results: More typical colony and form of the induced bacteria were obtainal when the three drugs had a concentration of 40 mg or 50 mg per pill. Conclusion: The three kinds of drug can change Bacillus dysenteriae and Bacillus coli into L-type bacteria,including that it must be made sure whether bacteria L develop when the clinical treatmant for acute or chronic infections with the traditional Chinese herbs does not work .Necessary drug regulation shoud be done to avoid the progression and relapse if there is the development or L-type bacteria.
出处
《郧阳医学院学报》
1999年第2期74-75,共2页
Journal of Yunyang Medical College
关键词
中药
细菌L型
诱导
药敏试验
筛选
Rhevm Palmatum
Coptis Chinensis
Salvia Miltiorrhiza
Radix Isatidis
L Forms
Microbiol Sensitivity Tests
