摘要
目的观察光学相干断层扫描(OCT)对泪河面积测量的应用,探讨其在干眼症诊断中的作用。方法对水液缺乏性干眼症和正常人各40人(40只眼)作为实验组和对照组,分别进行泪液分泌实验I、泪膜破裂时间、主观症状评分和OCT测量泪河面积。结果泪液分泌实验I:干眼症组7.26±2.85 mm,对照组20.03±5.39 mm;泪膜破裂时间:干眼症组3.57±2.46 s,对照组:10.64±5.37 s;症状评分:干眼症组1.92±1.12分,对照组0.71±0.93分;泪河面积平均值:干眼症组0.0110±0.0051 mm2,对照组0.0294±0.0186 mm2。两组4项指标差异均有统计学意义(P<0.01),泪河面积值与Schirmer试验结果呈正相关(r=0.94,P<0.001)。结论 OCT作为一种安全、快捷、非侵入性的检查方式,通过测量泪河面积的大小,对干眼症的诊断准确性高,可行性好。
Objective To observe the application of optical coherence tomography （OCT） in measurement of tear river area, and to discuss its application in diagnosis of dry eye syndrome. Methods A total of 40 patients （40 eyes） with dry eye syndrome due to deficiency of aqueous tear were allocated in trial group and 40 normal persons （40 eyes） as control group. Schirmer I Test ,Tear Break Up Time, subjective symptom scores and OCT measurement of tear fiver area were carried out for both groups. Results Schirmer I Test was 7.26 ± 2.85 mm in dry eye syndrome group and 20.03 ± 5.39 mm in control group ; Tear Break Up Time was 3.57 ± 2.46 s in dry eye syndrome group and 10.64 ± 5.37 s in control group. Symptom scores were 1.92 ± 1.12 points in dry eye syndrome group and 0. 71±0.93 points in control group. The average area of tear fiver was 0.0110± 0. 0051 mm2 in dry eye syndrome group, and it was 0. 0294 ± 0. 0186 mm2 in control group. The difference in 4 indicators between these two groups was statistically significant （ P 〈 0.01 ）. The value of tear fiver area had positive correlation with Schirmer test results （ r = 0.94, P 〈 0. 001 ）. Conclusion Optical coherence tomography can be conveniently used as a safe, efficient, non - invasive cheek way for measuring the size of the fiver of tears, and it is accurate and highly feasible in diagnosis of dry eye syndrome.
出处
《临床和实验医学杂志》
2011年第14期1060-1061,共2页
Journal of Clinical and Experimental Medicine
