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滋阴平肝潜阳汤调治正常高值血压的Logistic回归分析 被引量:1

Logistic Regression Analysis of Ziyin Pinggan Qinayang Decoction for Treating High-Normal Blood Pressure
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摘要 目的:观察滋阴平肝潜阳汤调治阴虚阳亢型正常高值血压的临床疗效。方法:前瞻性、随机对照临床研究。共收集阴虚阳亢型正常高值血压者200例,所有病例随机分为治疗组(100人)与对照组(100人),分别用滋阴平肝潜阳汤和杞菊地黄丸治疗,并观察两组患者治疗前后血压水平、证候疗效、血脂、血糖等。结果:最终选入两组药物、年龄、血糖3个变量,此3个变量的wald检验的P值分别为0.001、0.004、0.029,均有显著统计学意义,药物与降压疗效呈正相关,治疗组药的"疗效优势"为对照组药的5.674倍,同时年龄、血糖与降压疗效呈现出负相关。结论:滋阴平肝潜阳汤是治疗阴虚阳亢型正常高值血压的有效方药,不但能降低血压、改善症状,还有降血脂作用。 Objective:To observe clinical effects of Ziyin Pinggan Qinayang decoction for high-normal blood pressure belongs to type of deficiency of YIN leading to hyper activity of YANG.Methods:Prospective,random contrast clinical study.We observed 200 patients with high-normal blood pressure belong to type of deficiency of YIN leading to hyper activity of YANG,these patients were divided randomly into treatment group(100 cases) and control group(100 cases),and respectively treated by Ziyin Pinggan Qinayang decoction and Qiju Dihuang Pill,and observe blood pressure levels,therapeutic effect of syndrome,blood lipids,blood glucose,etc of patients in the two group before and after treatment.Results:3 variances of drug,age,blood glucose were selected in two groups,P value of these by wald test respectively was 0.001,0.004,0.029,and have remarkable statistical significance,drug was positively correlated with antihypertensive effect,therapeutic effect ascendancy of treatment group was 5.674 times that of control group,meanwhile,age and blood glucose were negative correlation with Antihypertensive effect.Conclusion:Ziyin Pinggan Qinayang decoction is effective for high-normal blood pressure belong to type of deficiency of YIN leading to hyper activity of YANG,it not only lower blood pressure,improve symptom,but also lower blood lipids.
出处 《辽宁中医杂志》 CAS 北大核心 2011年第7期1303-1305,共3页 Liaoning Journal of Traditional Chinese Medicine
关键词 滋阴平肝潜阳汤 正常高值血压 LOGISTIC回归分析 临床研究 Ziyin Pinggan Qinayang decoction high-normal blood pressure logistic regression analysis clinical study
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  • 1郑筱萸主编..中药新药临床研究指导原则 试行[M].北京:中国医药科技出版社,2002:392.
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