摘要
植物生长发育的许多过程都受到泛素-蛋白酶体途径的调控.泛素-蛋白酶体途径包括两个连续的过程:泛素化系统将底物蛋白泛素化;26s蛋白酶体降解泛素化的靶蛋白.其中泛素化系统对底物的泛素化是通过三种关键酶即泛素活化酶、泛素结合酶和泛素连接酶的连接级联反应完成的.这三类酶通过泛素介导的蛋白质选择性降解参与植物光形态建成、配子体发育、花发育、种子发育、激素的信号转导、抗逆、抗虫等方面的调控.
Most of the plant growth and development are regulated by the ubiquitin-proteasome pathway.The ubiquitin-proteasome pathway（UPP） consists of two major components： the ubiquitination system attaching a ubiquitin or a polyubiquitin chain to a substrate,and the 26S proteasome responsible for the degradation of protein substrates tagged by the polyubiquitin chain.Ubiquitin attachment is a multistep reaction involving three enzymes referred to as E1（ubiquitin-activating enzyme）,E2（ubiquitin-conjugating enzyme）,and E3（ubiquitin-protein ligase）.Their known biological functions include photomorphogenesis,gametogenesis,floral development,seed development,hormone signaling,responses to biotic and abiotic challenges.
出处
《济宁学院学报》
2011年第3期52-55,共4页
Journal of Jining University
基金
与南京农业大学合作项目
济宁市优秀中青年科研创新资金计划
济宁学院科研基金项目(2009KJLX07)
关键词
泛素蛋白酶体途径
泛素化系统
E1泛素活化酶
E2泛素结合酶
E3泛素连接酶
ubiquitin-proteasome pathway
ubiquitination system
E1 ubiquitin-activating enzyme
E2 ubiquitin-conjugating enzyme
E3 ubiquitin ligase
