摘要
目的探讨氯胺酮联合丙泊酚、瑞芬太尼用于小儿全凭静脉麻醉的效果及安全性。方法将2009年10月—2010年10月收治的ASA Ⅰ～Ⅱ级手术患儿60例随机分为治疗组和对照组,每组30例。对照组微量泵输注氯胺酮+丙泊酚混合剂;治疗组微量泵输注氯胺酮+丙泊酚+瑞芬太尼混合剂。记录2组患儿麻醉药物用量、术毕苏醒时间和麻醉期间呼吸、循环情况,观察术中镇静镇痛效果及不良反应发生情况。结果治疗组与对照组相比,用药量少,术毕苏醒快,镇静镇痛完善,对呼吸、循环的抑制小。结论氯胺酮联合丙泊酚、瑞芬太尼用于小儿全凭静脉麻醉疗效优于氯胺酮复合丙泊酚。
Objective To evaluate the efficacy and safety of ketamine combined with propofol and remifentanil in total intravenous anesthesia in children. Methods Sixty patients underwent pediatric surgery with ASA I - II grade from October 2009 to October 2010 were randomly divided into treatment group and control group,with 30 cases in each group. The patients in control group received propofol and ketamine mixture by micro pump infusion, while the treatment group received ketamine, propofol and remifentanil mixture. The dosage of anesthesia drug, postoperative recovery time, circulatory and respiratory status, effect of sedation and analgesia, and adverse reactions were recorded and compared. Results The treatment group was in lower dosage of anesthesia drug, more rapid postoperative recovery, better sedation and analgesia, smaller inhibition for circulatory and respiratory than those of the control group. Conclusion The effect of ketamine combined with propofol and remifentanil for total intravenous anesthesia in children is better than propofol cimbined with ketamine.
出处
《河北医科大学学报》
CAS
2011年第6期663-665,共3页
Journal of Hebei Medical University
关键词
氯胺酮
二异丙酚
瑞芬太尼
麻醉
静脉
ketamine
propofol
remifentanil
anesthesia, intravenous
