摘要
目的:观察70岁以上老年急性心肌梗死(AMI)的静脉溶栓疗效。方法:60例>70岁AMI患者(病例组)采用尿激酶静脉溶栓,与同期62例≤69岁的AMI患者作对照。观察患者末梢血嗜酸粒细胞计数,比较两组再通率及溶栓后并发症发生率。结果:老年AMI患者末梢血嗜酸粒细胞计数减少。两组患者>24小时溶栓者5例,无1例再通。两组<12小时溶栓再通率无明显差异,溶栓后并发症发生率差异无显著性。结论:对老年AMI患者静脉溶栓仍是安全有效的治疗方法,年龄不是静脉溶栓疗法的严格限制因素,AMI静脉溶栓的时间窗可以限制在<24小时。
Objective：To observe the curative effects of in travenous thrombolysis on senile patients with acute myocardial infarction （AMI） aged more than 70. Methods：60 cases with AMI aged more than70 （treatedgroup ） were treated with intravenous thrombolysis using urokinase and at the same time 62 cases aged less than 69 were choosen as control group. The eosinophil granulocyte countinperiphral blood and the concentrations of cortisol in blood in patients were observed, we can alizationrate and occurrance rate of complications after thrombolysis in two groups were compared. Resuits ：The eosinophil granulocyte countin senile patients was decreased but the concentration of cortisol was hightened. In two groups among 5 cases who received in travenous thrombolysis over 24 hours after attack of AMI and no one was repatency, we can alization rates in two groups had no obvious difference if the thromolysis was carried outwithin 12 hours mean while the occurrance rates of complications after thrombolysis had not marked difference, too. Conclusions ： The treatment within travenous thrombolysis for senile patients with AMI is still safe and effective. The age is not astrict factor to limit the use of intravenous thrombolysis. The time window of thrombolysis for patients with AMI should be stricted in 24 hours.
关键词
急性心肌梗死
静脉溶栓
老年人
嗜酸粒细胞
Acute - myocardial infarction
Intravenous thrombolysis
Senile
eosinophil
