摘要
采用酶联免疫法检测２４ 例肺心病患者和３０ 例健康中老年人的尿视黄醇结合蛋白 （ＲＢＰ）， 转铁蛋白（ＴＲＦ） 水平。同时测定其血尿素氮（ＢＵＮ）， 肌酐 （Ｃｒ）。结果： 肺心病患者尿ＲＢＰ、ＴＲＦ水平较对照组显著升高 （Ｐ＜ ０．０１），其中合并心衰患者较无合并心衰者的尿ＲＢＰ、ＴＲＦ水平有显著性差异（Ｐ＜ ０．０１）。表明患肺心病患者确存在肾功能的损害， 动态观察尿ＲＢＰ、ＴＲＦ水平变化是判断其早期肾功能损害的敏感方法，
The levelof retinal-binding-protein (RBP) and transferrin (TRF) w as m easured by using ELISA in urine of 24 patients w ith cor pulm onale and 30 health subjects. It w as found that the levels of RBP and TRFin the patients w ith cor pulm onale w ere significantly higher than in health subjects (P< 0.01) . RBP and TRF levels in the cor pulm onale patients associated w ith right heart breakdow n w ere greatly differentfrom those w ithoutheartbreakdow n (P< 0.01). The results show ed thatthe dam ages to kidney function in the patients w ith corpulm onale existed indeed. The dynam ic observation ofthe levels of RBPand TRFw as a sentive m ethod for estim ating early renalfunction dam age.
出处
《同济医科大学学报》
CSCD
1999年第5期405-406,共2页
Acta Universitatis Medicinae Tongji
