摘要
目的探讨如意金黄散的微生物限度检查方法。方法按《中国药典》2010年版微生物限度检查法进行验证和试验。结果经方法学验证实验得出,如意金黄散有抑菌作用,其微生物限度检查计数方法采用培养基稀释法(0.5mL/皿,1∶20的供试液),控制菌检查按培养基稀释法(铜绿假单孢菌采用100mL BL增菌液;金黄色葡萄球菌采用200mL营养肉汤,1∶20的供试液)进行。结论经验证该微生物限度检查方法适用于如意金黄散的微生物限度检查。
Objective T0 establish the method of microbial limit test for Ruyi Jinhuang San. Methods The validation test was carried out according to Chinese Pharmacopoeia （Chp 2010）. Results The results of validation test showed Ruyi Jinhuang San had antibacterial activity. The culture media dilution method was used as the counting methods for the bacteria, moulds and yeasts （0.5mL/dish, 1 ： 20 sample solution） and the eontrolled bacteria detection test. Conclusion This method is feasible for the microbial limit test of Ruyi Jinhuang San.
出处
《中国现代医生》
2011年第19期97-98,共2页
China Modern Doctor
关键词
微生物限度检查
验证
如意金黄散
Microbial limit test
Validation
Ruyi Jinhu.ang San
