摘要
[目的]研究温州市居民高尿酸血症(HUA)的流行特征。[方法]采用多阶段随机抽样方法抽取温州市瑞安、瓯海两个区3 502例≥35岁常住居民进行面对面问卷调查、体格检查及实验室检查。测量调查对象的身高、体重、血压,测定空腹血糖、血总胆固醇、三酰甘油、高密度脂蛋白胆固醇和低密度脂蛋白胆固醇、尿酸。[结果]温州市居民尿酸均值为(260.25±93.21)μmol/L,高尿酸血症率为7.47%,男、女分别为10.78%、4.93%;代谢综合征(MS)的患病率为17.90%。HUA组MS患病率为34.62%,尿酸正常组为16.55%(P<0.01)。HUA组MS组分高血压、高血糖、低高密度脂蛋白、高三酰甘油、肥胖比例分别为62.31%、26.15%、13.46%、67.31%、46.92%,明显高于尿酸正常组。多因素Logistic回归分析显示,HUA与男性、饮酒、年龄(>65岁)、肥胖、高低密度脂蛋白、高三酰甘油密切相关。[结论]温州市HUA患病率为7.47%,HUA与MS的主要组分肥胖、高低密度脂蛋白、高甘油三酯密切相关,做好HUA早期干预至关重要。
[Objective] To study the epidemiological characteristics of hyperuricemia（HUA） in Wenzhou City. [Methods] By means of multistage stratified cluster sampling method 3 502 residents over 35 years old from 2 communities were investigated with questionnaire and received physical examination and lab tests.And then the relationship between serum uric acid and the chief parameters of the metabolic syndrome was observed. [Results] The mean serum uric acid of the residents investigated was（260.25±93.21）μmol/L.The prevalence of hyperuricemia in the two community population was 7.47%,which was higher in men（10.78%）,compared with that in women（4.93%）;The prevalence rate of the MS was 17.90%.The prevalence rate of hypertension,diabetes,low HDL-cholesterol,High triglycerides,Overweight and Obesity was 62.31%,26.15%,13.46%,67.31%,46.92% in hyperuricemia group,which were much higher than those in normal UA group,By using logistic regression analysis it was shown that serum uric acid levels was correlated with triglycerides,HDL-cholesterol,body mass index,drinking,and so on. [Conclusion] The prevalence of hyperuricemia and the metabolic syndrome in Wenzhou was 7.47% and 14.6% respectively,suggesting that hyperuricemia might be one of the risk factors for metabolic syndrome.
出处
《上海预防医学》
CAS
2011年第6期257-260,共4页
Shanghai Journal of Preventive Medicine
基金
温市科技[2008]5号
编号:Y20080093
关键词
高尿酸症
代谢综合征
流行特征
患病率
Hyperuricemia
Metabolic syndrome
Epidemiological characteristics
Prevalence
