摘要
目的探讨彩色多普勒超声检测叶间动脉血流动力学参数对慢性肾疾病（chronic kidney disease，CKD）的早期诊断价值。方法运用彩色多普勒超声对78例CKD患者和65例健康人的叶间动脉进行超声检查，测量收缩期峰值流速（PSV）、舒张末期血流速度（EDV）、搏动指数（PI）、阻力指数（RI），同时进行血清胱抑素C（SCysC）的检测，观察早期CKD患者叶间动脉RI的变化规律并分析其与肾活检病理结果的相关性。结果40例SCysC正常的CKD患者（A组）叶间动脉PSV、EDV、PI、RI与正常对照组比较差异无统计学意义（P〉0．05）；38例SCysC增高的CKD患者（B组）叶间动脉RI明显高于A组和正常对照组（P〈0．05），PSV、EDV均明显低于A组和正常对照组（P〈0．05）。RI正常者病变仅局限于肾小球，RI增高者病变已累及肾小管间质。结论叶间动脉RI联合SCysC是评估CKD患者肾早期损害的敏感指标。
Objective To explore the value of color Doppler ultrasound detection renal interlobar arterial hemodynamic parameters for early diagnosis in patients with chronic kidney disease（CKD）. Methods Seventy-eight patients with CKD were undergone interlobar arterial hemodynamic parameters deicection and 65 normal persons served as the control. The peak systolic velocity （PSV）, end-diastolic velocity （EDV）, pulsatility index（H）, resistive index （RI） of interlobar arterial and serum cystatin C （SCysC） were measured. The variation of RI and the correlation of renal interlobar arterial RI and pathological findings in early CKD was analyzed. Results In 40 CKD cases with normal SCysC（group A）,the PSV,EDV,PI,RI of renal interlobar arterial were not statistically significant （ P 〉0.05）. In 38 CKD cases with increased SCysC （group B） ,the RI of renal interlobar arterial were higher than those of group A and control group （ P 〈 0.05） ,and the PSV and EDV were lower than those of group A and control group （ P 〈0.05）. In cases of CKD with normal RI,the disease limited to the glomeruli; while the RI increased, the disease locate in the tubulointerstitial compartment. Conclusions Interlobar arterial RI united SCysC is a sensitive indicator in assessing early injury of chronic kidney disease.
出处
《中华超声影像学杂志》
CSCD
北大核心
2011年第6期508-510,共3页
Chinese Journal of Ultrasonography
关键词
超声检查
多普勒
彩色
肾疾病
叶间动脉
血液动力学现象
Ultrasonography, Doppler, color
Kidney disease
Interlobar arterial
Hemodynamic phenomena
